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Table 4 Multivariate analysis for disease-free survival and overall survival in the AYA and non-AYA groups

From: Outcomes of adolescent and young patients with hepatocellular carcinoma after curative liver resection: a retrospective study

  Disease-free survival Overall survival
HR 95% CI P value HR 95% CI P value
AYA group
 Maximum tumor size > 5 cm 1.3 1.1–2.4 < 0.01 1.5 1.1–2.7 < 0.01
 Portal vein invasion 1.8 1.5–2.3 < 0.01 1.6 1.4–2.4 < 0.01
 Tumor capsule formation 0.6 0.3–0.8 < 0.05    
 TNM stage 2.1 1.5–3.1 < 0.01 3.1 2.1–5.4 < 0.01
 AFP > 100 ng/dL     1.4 1.1–2.5 < 0.01
Non-AYA groups
 Maximum tumor size > 5 cm 1.5 1.2–2.1 < 0.01 1.7 1.2–2.6 < 0.01
 Portal vein invasion 2.1 1.3–3.3 < 0.01 2.5 1.4–3.5 < 0.01
 Satellite nodules 1.9 1.3–2.7 < 0.05    
 Tumor capsule formation 0.5 0.2–0.9 < 0.05 0.7 0.3–0.9 < 0.01
 TNM stage 2.7 1.3–4.1 < 0.01 1.8 1.1–3.1 < 0.01
 AFP > 100 ng/dL     2.0 1.2–4.1 < 0.05