Table 1 The clinical and histologic characteristics of primary cohort

 0, ≤ 50 years

91

33

58

1

 1, > 50 years

230

103

127

0.702 (0.425–1.157)

0.164

 0, Male

273

115

158

1

 1, Female

48

21

27

0.936 (0.504–1.738)

0.834

 0, ≤ 20 ng/mL

144

84

60

1

 1, > 20 ng/mL

177

52

125

3.365(2.118–5.347)

< 0.001

 0, absent

301

130

171

1

 1, present

20

6

14

1.774 (0.664–4.741)

0.248

 0, absent

77

33

44

1

 1, present (HBV/HCV)

244

103

141

1.027 (0.612–1.723)

0.921

 0, absent

84

41

43

1

 1, present

237

95

142

1.425 (0.864–2.351)

0.164

 0, ≤ 40 U/L

229

108

121

1

 1, > 40 U/L

92

28

64

2.040 (1.220–3.412)

0.006

 0, ≤ 40 U/L

226

111

115

1

 1, > 40 U/L

95

25

70

2.703 (1.597–4.573)

< 0.001

 0, ≤ 50 U/L

151

73

78

1

 1, > 50 U/L

170

63

107

1.590 (1.018–2.482)

0.041

 0, ≤ 19 μmol/L

274

116

158

1

 1, > 19 μmol/L

47

20

27

0.991 (0.530–1.853)

0.978

 0, ≤ 6.8 μmol/L

244

107

137

1

 1, > 6.8 μmol/L

77

29

48

1.293 (0.764–2.187)

0.338

 0, ≤ 40 g/L

91

40

51

1

 1, > 40 g/L

230

96

134

1.095 (0.671–1.787)

0.717

 0, ≤ 100*10⁹/L

40

19

21

1

 1, > 100*10⁹/L

281

117

164

1.268 (0.653–2.464)

0.483

 0, ≤ 1.0

180

84

96

1

 1, > 1.0

141

52

89

1.498 (0.955–2.349)

0.078

 0, ≤ 12 s

241

105

136

1

 1, > 12 s

80

31

49

1.220 (0.728–2.046)

0.45

Surgical size (cm)

321

4 (3–6)

6.3 (4.5–9.25)

< 0.001

 0, incomplete

194

88

106

1

 1, complete

127

48

79

1.366 (0.865–2.157)

0.18

 I–II

141

77

64

1

 III–IV

180

59

121

2.467 (1.566–3.888)

< 0.001