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Fig. 3 | World Journal of Surgical Oncology

Fig. 3

From: Verification of genetic differences and immune cell infiltration subtypes in the neuroblastoma tumour microenvironment during immunotherapy

Fig. 3

Distinguishing immune-related gene subtypes. A The DEGs in different groups were divided into three groups by unsupervised cluster analysis as gene Clusters A–C. B The distribution of infiltrating immune cells in different NB subtypes. C, D Gene ontology (GO) enrichment analysis of notable genes of different ICI subtypes: ICI notable genes. E Association between different NB subgroups and overall survival, p = 0.04. F Differences in infiltrating immune cells, immune scores and matrix scores of different NB gene subtypes. NS, no significance; ***p < 0.001; **p < 0.01; *p < 0.05. G, H The distribution of CTLA4 and PD-L1 expression among different ICI genotypes (p < 0.001)

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