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Table 1 Correlation between tumoral B7-H3 and clinicopathological features of LUAD patients

From: B7-H3 is eligible for predicting clinical outcomes in lung adenocarcinoma patients treated with EGFR tyrosine kinase inhibitors

 

n (%)

B7-H3 expression

P

low

high

Age (years)

   

0.485

 <60

24 (42.9%)

12 (38.7%)

12 (48.0%)

 

 ≥60

32 (57.1%)

19 (61.3%)

13 (52.0%)

 

Gender

   

0.320

 Male

31 (55.4%)

19 (61.3%)

12 (48.0%)

 

 Female

25 (44.6%)

12 (38.7%)

13 (52.0%)

 

Tumor size (mm)

   

0.651

 ≤30

22 (39.3%)

13 (41.9%)

9 (36.0%)

 

 >30

34 (60.7%)

18 (58.1%)

16 (64.0%)

 

Pathological stage

   

0.089

 III

16 (28.6%)

6 (19.4%)

10 (40.0%)

 

 IV

40 (71.4%)

25 (80.6%)

15 (60.0%)

 

EGFR mutation

   

0.931

 19 Del

31 (55.4%)

17 (54.8%)

14 (56.0%)

 

 21 L858R

25 (44.6%)

14 (45.2%)

11 (44.0%)

 

EGFR-TKIs

   

0.839¶

 Gefitinib

30 (53.6%)

16 (51.6%)

14 (56.0%)

 

 Icotinib

22 (39.3%)

12 (38.7%)

10 (40.0%)

 

 Erlotinib

4 (7.1%)

3 (9.7%)

1 (4.0%)

 
  1. ¶Fisher’s exact test in RxC contingency tables