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Table 2 A compilation of reported cases of intestinal metastases from choriocarcinoma published in English from 1933 to the present

From: Intestinal metastasis from choriocarcinoma: a case series and literature review

 

Age

Symptoms

Time until last pregnancy

hCG level before treatment (IU/mL)

Metastatic lesions

Primary uterine lesion

Treatment

Outcome

Bin Chet Toh (2020) [10]

Fatemi SR (2017) [11]

38 y

33 y

melanorrhagia

Abdominalgia, melanorrhagia

Not available

5 years

6,764

57,000

Jejunum, lung

Jejunum

No

Yes

Selective coil vascular embolization, chemotherapy

Jejunum lesion resection and anastomosis, chemotherapy

Not available

Alive

En Bee Cho (2016) [5]

40 y

Abdominalgia, vaginal bleeding

2 years

8,837

Jejunum, lung, liver

No

Jejunum lesion resection and anastomosis, diagnostic curettage, EMA-CO

Alive

Anisha Ramessur (2015) [12]

32 y

melanorrhagia, anemia

5 years

77,000

Jejunum, lung, liver

YES

EP chemotherapy

Alive

Anil Arora (2013) [13]

31 y

Lower GI bleeding

5 months

25,000

Proximal ileum, cecum, ascending colon, sigmoid, rectum

Yes

Ileal lesion resection and anastomosis

Not available

Bokhari (2009) [14]

35 y

Lower GI bleeding

1 month

Not available

Terminal ileum, lung, spleen, kidney, posterior mediastinum

No

Ileal lesion resection and anastomosis

Not available

M Chaturvedi (2005) [15]

30y

Weakness, fatiguability, giddiness, breathlessness, and palpitations

6 months

Not available

Ileum, descending colon, lung, liver, pancreas, right kidney

No

Not available

Died 5 days after admitted to hospital

PG Balagopal (2003) [16]

32 y

Abdominalgia, vomiting

Not available

Not available

Jejunum, lung, liver, brain

No

Small bowel resection and anastomosis, EMA-CO/BEP

Not available

Bina Ravi (1997) [17]

22 y

Fever, vomiting, abdominal distention

Not available

Not available

Small bowel, liver, spleen

No

Small bowel resection and anastomosis

Died 8 days after surgery

I.T. Magrath (1971) [18]

23y

melanorrhagia

1 month

> 1,000,000 IU/day

Proximal ileum, ampulla of Vater, lung, liver

No

Small bowel resection and anastomosis

Died 7 months after treatment

Sear JB (1933) [19]

32y

melanorrhagia, weakness

3 years

Not available

Jejunum, omentum, liver

No

Small bowel resection and anastomosis, X-ray treatment

Died 1 month after surgery