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Table 4 Univariate and multivariate survival analyses of clinicopathological characteristics

From: Defective expression of C20orf54 in esophageal dysplasia: a possible biomarker of esophageal carcinoma for early detection

Characteristics

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

C20orf54 defective expression

2.044 (0.912,4.583)

0.082

1.522 (0.642, 3.608)

0.340

Differentiationa (poor)

1.490 (0.775,2.865)

0.232

1.256 (0.599, 2.635)

0.546

TNMb (III+IV)

2.108 (1.190,3.733)

0.011*

2.519 (1.043, 6.082)

0.040*

L/N metastasis (positive)

2.429 (1.369,4.308)

0.002*

0.910 (0.368, 2.247)

0.838

Invasion depth (T2, T3, T4)

5.24 (1.626,16.935)

0.006*

5.817 (1.542, 21.94)

0.009*

Location (upper, middle)

1.906 (1.029,3.531)

0.040*

1.859 (0.970, 3.564)

0.062

Smokers (ever)

0.966 (0.534,1.748)

0.909

0.93 (0.437, 1.988)

0.856

Drinkers (ever)

1.107 (0.629,1.949)

0.724

0.84 (0.436, 1.768)

0.715

  1. L/N lymph node metastasis, HR hazard radio, CI confidence interval of the estimated HR. aHistologic grade was based on a World Health Organization classification published in 2019 [16]. bTNM stage was based on the American Joint Committee on Cancer Q1 criteria published in 2017 [14]