Skip to main content

Table 6 Univariate and multivariate analyses of prognostic factors for OS in advanced-stage diseases

From: Differential roles of the Wip1–p38–p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas

Stages III–IV (n=41) Univariate Multivariate
  HR 95% CI p-value HR 95% CI p-value
High Wip1 4.93 1.70–14.3 0.0033 3.98 1.38–11.5 0.011
Positive p53 0.98 0.40–2.40 0.96 - - -
High phospho-p53 0.35 0.10–1.21 0.097 - - -
High nuclear phospho-p38 7.86E+07 0–Inf 1.00 - - -
High cytoplasmic phospho-p38 0.48 0.20–1.14 0.096 - - -
Age ≥60 0.46 0.17–1.25 0.13 - - -
Positive peritoneal cytology 1.03 0.30–3.48 0.96 - - -
Residual tumor present 2.72 1.45–6.48 0.024 2.39 0.98–5.79 0.055
Endometriosis present 0.82 0.34–1.96 0.66 - - -
Lymphadenectmy undone 1.62 0.70–3.75 0.26 - - -
Adjuvant chemotherapy performed NA NA NA - - -
Pure histology 1.79 0.42–7.66 0.43 - - -
  1. OS overall survival, HR hazard ratio, CI confidence interval, Inf infinity, NA not applicable