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Table 5 Univariate and multivariate analyses of prognostic factors for OS in early-stage diseases

From: Differential roles of the Wip1–p38–p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas

Stages I–II (n=102) Univariate   Multivariate
  HR 95% CI p-value HR 95% CI p-value
High Wip1 0.58 0.13–2.51 0.46 - - -
Positive p53 2.48 0.92–6.65 0.071 - - -
High phospho-p53 2.43 0.32–18.3 0.39 - - -
High nuclear phospho-p38 1.00 0.39–2.51 0.99 - - -
High cytoplasmic phospho-p38 1.56 0.36–6.81 0.56 - - -
Age ≥ 60 1.70 0.46–3.60 0.64 - - -
Positive peritoneal cytology 8.23 2.93–23.2 0.00065 9.25 3.19–26.9 0.00043
Residual tumor present 9.62 1.21–76.3 0.032 21.7 2.28–205.4 0.0074
Endometriosis present 1.07 0.41–2.76 0.89 - - -
Lymphadenectmy undone 2.69 0.96–7.56 0.060 - - -
Adjuvant chemotherapy performed 1.07 0.14–8.10 0.94 - - -
Pure histology 0.29 0.038–2.18 0.23 - - -
  1. OS overall survival, HR hazard ratio, CI confidence interval