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Table 5 Univariate and multivariate analyses of prognostic factors for OS in early-stage diseases

From: Differential roles of the Wip1–p38–p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas

Stages I–II (n=102)

Univariate

 

Multivariate

 

HR

95% CI

p-value

HR

95% CI

p-value

High Wip1

0.58

0.13–2.51

0.46

-

-

-

Positive p53

2.48

0.92–6.65

0.071

-

-

-

High phospho-p53

2.43

0.32–18.3

0.39

-

-

-

High nuclear phospho-p38

1.00

0.39–2.51

0.99

-

-

-

High cytoplasmic phospho-p38

1.56

0.36–6.81

0.56

-

-

-

Age ≥ 60

1.70

0.46–3.60

0.64

-

-

-

Positive peritoneal cytology

8.23

2.93–23.2

0.00065

9.25

3.19–26.9

0.00043

Residual tumor present

9.62

1.21–76.3

0.032

21.7

2.28–205.4

0.0074

Endometriosis present

1.07

0.41–2.76

0.89

-

-

-

Lymphadenectmy undone

2.69

0.96–7.56

0.060

-

-

-

Adjuvant chemotherapy performed

1.07

0.14–8.10

0.94

-

-

-

Pure histology

0.29

0.038–2.18

0.23

-

-

-

  1. OS overall survival, HR hazard ratio, CI confidence interval