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Table 2 The optimal cut-off values of IHC scores for the relationships with OS

From: Differential roles of the Wip1–p38–p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas

  Mean±SD Stage I/II   Stage III/IV
  Cut-off Category N (%) Cut-off Category N (%)
Wip1 0.6±1.1 1< High 18 (18) 1< High 5 (12)
Low 84 (82) Low 36 (88)
P53 8.7±16.8 10%≤ Positive 21 (21) 10%≤ Positive 14 (34)
Negative 81 (79) Negative 27 (66)
Phospho-p53 5.3±2.7 2< High 57 (56) 0< High 38 (93)
Low 45 (44) Low 3 (7)
Nuclear phospho-p38 7.4±1.7 6< High 50 (49) 5< High 38 (93)
Low 52 (51) Low 3 (7)
Cytoplasmic phospho-p38 3.4±2.8 8< High 9 (9) 1< High 30 (73)
Low 93 (91) Low 11 (27)
  1. IHC immunohistochemical, OS overall survival, SD standard deviation