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Table 2 The optimal cut-off values of IHC scores for the relationships with OS

From: Differential roles of the Wip1–p38–p53 DNA damage response pathway in early/advanced-stage ovarian clear cell carcinomas

 

Mean±SD

Stage I/II

 

Stage III/IV

 

Cut-off

Category

N (%)

Cut-off

Category

N (%)

Wip1

0.6±1.1

1<

High

18 (18)

1<

High

5 (12)

Low

84 (82)

Low

36 (88)

P53

8.7±16.8

10%≤

Positive

21 (21)

10%≤

Positive

14 (34)

Negative

81 (79)

Negative

27 (66)

Phospho-p53

5.3±2.7

2<

High

57 (56)

0<

High

38 (93)

Low

45 (44)

Low

3 (7)

Nuclear phospho-p38

7.4±1.7

6<

High

50 (49)

5<

High

38 (93)

Low

52 (51)

Low

3 (7)

Cytoplasmic phospho-p38

3.4±2.8

8<

High

9 (9)

1<

High

30 (73)

Low

93 (91)

Low

11 (27)

  1. IHC immunohistochemical, OS overall survival, SD standard deviation