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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Ring finger protein 180 suppresses cell proliferation and energy metabolism of non-small cell lung cancer through downregulating C-myc

Fig. 2

Overexpression of RNF180 decreased the activity of glycolysis and proliferation of human H292 cells. A Functional analysis indicated that RNF180 was enriched in glycolysis metabolism in NSCLC. B Overexpression of RNF180 significantly suppressed the level of ECAR in NSCLC cells. C CCK8 assay was performed to examine the proliferation of oeNC and oeRNF180 transfecting cells respectively. D Western blot was used to examine the protein levels of C-myc, HK2, and LDHA in oeNC and oeRNF180 transfecting cells

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