Skip to main content

Table 1 Patient characteristics according to CRLM status (resected or unresected)

From: Prognostic factors of BRAF V600E colorectal cancer with liver metastases: a retrospective multicentric study

Variables Total (n = 105) Resected CRLM (n = 49) Unresected CRLM (n = 56) P value
Gender
 Male 51 (49%) 20 (41%) 31 (55%) 0.1369
 Female 54 (51%) 29 (59%) 25 (45%)
Age
65 years 42 (40%) 20 (41%) 22 (39%) 0.8731
>65 years 63 (60%) 29 (59%) 34 (61%)
Primary tumor site
 Right-sided 56 (55%) 26 (54%) 30 (56%) 0.0911
 Left-sided 28 (27%) 17 (36%) 11 (20%)
 Rectum 18 (18%) 5 (10%) 13 (24%)
 Missing data 3 1 2
Primary tumor surgery
 Yes 79 (75%) 49 (100%) 30 (54%) < 0.0001
 No 26 (25%) 0 26 (46%)
T stage
 T1–T2 4 (5%) 4 (8%) 0 0.2909
 T3–T4 73 (95%) 44 (92%) 29 (100%)
 Missing data 28 1 27
N stage
 N0 9 (12%) 7 (15%) 2 (7%) 0.4699
 N1–N2 68 (88%) 41 (85%) 27 (93%)
 Missing data 28 1 27
CRLM time of diagnosis
 Synchronous 94 (90%) 41 (84%) 53 (95%) 0.0671
 Metachronous 11 (10%) 8 (16%) 3 (5%)
CRLM distribution
 Unilobar 33 (39%) 21 (57%) 12 (26%) 0.0036
 Bilobar 51 (61%) 16 (43%) 35 (74%)
 Missing data 21 12 9
Number of CRLM
 <10 56 (70%) 32 (89%) 24 (55%) < 0.0001
10 24 (30%) 4 (11%) 20 (45%)
 Missing data 25 13 12
Initial resectability
 Yes 43 (52%) 32 (86%) 11 (24%) < 0.0001
 No 39 (48%) 5 (14%) 34 (76%)
 Missing data 23 12 11
RAS status
 Wild-type 103 (99%) 47 (98%) 56 (100%) 0.4615
 Mutant 1 (1%) 1 (2%) 0
 Missing data 1 1 -
MSI-H
 Yes 21 (30%) 14 (29%) 7 (33%) 0.7293
 No 48 (70%) 34 (71%) 14 (67%)
 Missing data 36 1 35
Resection margin status
 R0 32 (89%) 32 (89%) NC  
 R1 parenchymal 4 (11%) 4 (11%) NC
 R1 vascular 0 0 NC
 Missing data 13 13  
  1. CRLM Colorectal liver metastases, MSI-H Microsatellite instability. χ2 or Fisher’s exact test was applied for groups comparisons. NC Not concerned