Table 1 Patient characteristics according to CRLM status (resected or unresected)
Variables | Total (n = 105) | Resected CRLM (n = 49) | Unresected CRLM (n = 56) | P value |
|---|---|---|---|---|
Gender | ||||
Male | 51 (49%) | 20 (41%) | 31 (55%) | 0.1369 |
Female | 54 (51%) | 29 (59%) | 25 (45%) | |
Age | ||||
≤65 years | 42 (40%) | 20 (41%) | 22 (39%) | 0.8731 |
>65 years | 63 (60%) | 29 (59%) | 34 (61%) | |
Primary tumor site | ||||
Right-sided | 56 (55%) | 26 (54%) | 30 (56%) | 0.0911 |
Left-sided | 28 (27%) | 17 (36%) | 11 (20%) | |
Rectum | 18 (18%) | 5 (10%) | 13 (24%) | |
Missing data | 3 | 1 | 2 | |
Primary tumor surgery | ||||
Yes | 79 (75%) | 49 (100%) | 30 (54%) | < 0.0001 |
No | 26 (25%) | 0 | 26 (46%) | |
T stage | ||||
T1–T2 | 4 (5%) | 4 (8%) | 0 | 0.2909 |
T3–T4 | 73 (95%) | 44 (92%) | 29 (100%) | |
Missing data | 28 | 1 | 27 | |
N stage | ||||
N0 | 9 (12%) | 7 (15%) | 2 (7%) | 0.4699 |
N1–N2 | 68 (88%) | 41 (85%) | 27 (93%) | |
Missing data | 28 | 1 | 27 | |
CRLM time of diagnosis | ||||
Synchronous | 94 (90%) | 41 (84%) | 53 (95%) | 0.0671 |
Metachronous | 11 (10%) | 8 (16%) | 3 (5%) | |
CRLM distribution | ||||
Unilobar | 33 (39%) | 21 (57%) | 12 (26%) | 0.0036 |
Bilobar | 51 (61%) | 16 (43%) | 35 (74%) | |
Missing data | 21 | 12 | 9 | |
Number of CRLM | ||||
<10 | 56 (70%) | 32 (89%) | 24 (55%) | < 0.0001 |
≥10 | 24 (30%) | 4 (11%) | 20 (45%) | |
Missing data | 25 | 13 | 12 | |
Initial resectability | ||||
Yes | 43 (52%) | 32 (86%) | 11 (24%) | < 0.0001 |
No | 39 (48%) | 5 (14%) | 34 (76%) | |
Missing data | 23 | 12 | 11 | |
RAS status | ||||
Wild-type | 103 (99%) | 47 (98%) | 56 (100%) | 0.4615 |
Mutant | 1 (1%) | 1 (2%) | 0 | |
Missing data | 1 | 1 | - | |
MSI-H | ||||
Yes | 21 (30%) | 14 (29%) | 7 (33%) | 0.7293 |
No | 48 (70%) | 34 (71%) | 14 (67%) | |
Missing data | 36 | 1 | 35 | |
Resection margin status | ||||
R0 | 32 (89%) | 32 (89%) | NC | |
R1 parenchymal | 4 (11%) | 4 (11%) | NC | |
R1 vascular | 0 | 0 | NC | |
Missing data | 13 | 13 | ||