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Table 1 Baseline clinical characteristics of glioblastoma patients in original and PSM cohort

From: Prognostic significance of preoperative systemic inflammation response index in newly diagnosed glioblastoma patients underwent gross total resection: a propensity score matching analysis

Clinical characteristic

Original cohort

PSM cohort

Sample size

291 (100)

196 (100)

Overall survival

Mean ± SD (day)

435.6 ± 314.0

389.2 ± 282.8

Median (range)

355 (31–1580)

304 (31–1580)

Age at diagnosis

Mean ± SD (year)

53.7 ± 14.2

54.2 ± 13.8

Median (range)

54 (18–85)

55 (19–85)

Gender

Male

186 (63.9)

147 (75.0)

Female

105 (36.1)

49 (25.0)

Preoperative seizures

Yes

40 (13.7)

28 (14.3)

No

251 (86.3)

168 (85.7)

Karnofsky performance status

≤ 80

183 (62.9)

123 (62.8)

> 80

108 (37.1)

73 (37.2)

Hemisphere

Right

132 (45.4)

89 (45.4)

Left

144 (49.5)

98 (50.0)

Midline or bilateral

15 (5.1)

9 (4.6)

Location

Frontal lobe

98 (33.7)

60 (30.6)

Temporal lobe

59 (20.3)

43 (21.9)

Parietal lobe

26 (8.9)

18 (9.2)

Occipital lobe

8 (2.7)

3 (1.5)

Insular lobe

12 (4.1)

10 (5.1)

Other locations

88 (30.2)

62 (31.6)

Adjuvant therapy

Yes

230 (79.0)

156 (79.6)

No or undone

61 (23.0)

40 (20.4)

Ki-67

< 30%

170 (58.4)

119 (60.7)

≥ 30%

121 (41.6)

77 (39.3)

IDH-1

Mutant

42 (14.4)

27 (13.8)

Wildtype

249 (85.6)

169 (86.2)

SIRI

< 1.26

177 (60.8)

98 (50.0)

≥ 1.26

114 (39.2)

98 (50.0)

NLR

< 4.86

237 (81.4)

≥ 4.86

54 (18.6)

< 4.63

146 (74.5)

≥ 4.63

50 (25.5)

  1. Data are presented as n (%)
  2. Abbreviations: IDH-1 isocitrate dehydrogenase-1, SIRI systemic inflammation response index, NLR neutrophil to lymphocyte ratio, PSM propensity score matching