Representativeness of cases
|
Selected from population or cancer registry
|
3
|
Selected from hospital
|
2
|
Selected from pathology archives, but without description
|
1
|
Not described
|
0
|
Source of controls
|
Population based
|
3
|
Blood donors or volunteers
|
2
|
Hospital based (cancer-free patients)
|
1
|
Not described
|
0
|
Case-control match
|
Matched by age and gender
|
3
|
Not matched by age and gender
|
0
|
Specimens used for determining genotypes
|
White blood cells or normal tissues
|
3
|
Tumor tissues or exfoliated cells of tissue
|
0
|
Hardy–Weinberg equilibrium (HWE)
|
Hardy–Weinberg equilibrium in control subjects
|
3
|
Hardy–Weinberg disequilibrium in control subjects
|
0
|
Total sample size
|
> 1000
|
3
|
> 500 and < 1000
|
2
|
> 200 and < 500
|
1
|
< 200
|
0
|