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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: KIF14 affects cell cycle arrest and cell viability in cervical cancer by regulating the p27Kip1 pathway

Fig. 4

KIF14 knockdown results in cervical cancer cell cycle arrest. HeLa cells were transfected with si-NC, si-KIF14, NC OE, or KIF14 OE for 24 h. A The KIF14 and cyclin-associated protein levels were detected via western blot. B KIF14 knockdown or overexpression and the mRNA levels of Cyclin D1, Cyclin B1, p21, and p27. C HeLa cells were transfected with si-NC or si-KIF14 for 24 h and then treated with 2 μg/ml cycloheximide for 0 h, 0.5 h, 1 h, and 3 h. KIF14 knockdown inhibited p27 degradation. *p < 0.05, **p < 0.01, and ***p < 0.001

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