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Table 1 Clinical and pathological characteristics of rectal cancer patients who underwent TME with or without LPND before and after matching

From: Mesorectal excision with lateral lymph node dissection for mid-low rectal cancer with lateral lymph node metastasis: efficacy and prognostic analysis

Variables

Original cohort

Matched cohort

TME (n = 362)

TME + LPND (n = 129)

P

TME (n = 125)

TME + LPND (n = 125)

P

Gender

Ā Ā 

0.493

Ā Ā 

0.798

ā€ƒMale

195 (53.9)

74 (57.3)

Ā 

71 (56.8)

73 (58.4)

Ā 

ā€ƒFemale

167 (44.1)

55 (42.7)

Ā 

54 (43.2)

52 (41.6)

Ā 

Age (years)

Ā Ā 

0.869

Ā Ā 

0.899

ā€ƒ<ā€‰60

199 (55.0)

72 (55.8)

Ā 

68 (54.4)

69 (55.2)

Ā 

ā€ƒā‰„ 60

163 (45.0)

57 (44.2)

Ā 

57 (45.6)

56 (44.8)

Ā 

BMI (kg/m2)

24.0 Ā± 3.1

24.9 Ā± 3.2

0.081

24.5 Ā± 3.1

25.0 Ā± 3.1

0.226

ASA score

Ā Ā 

0.784

Ā Ā 

0.625

ā€ƒIā€“II

337 (93.1)

121 (93.8)

Ā 

115 (92.0)

117 (91.4)

Ā 

ā€ƒIII

25 (6.9)

8 (6.2)

Ā 

10 (8.0)

8 (8.6)

Ā 

Neoadjuvant therapy

Ā Ā 

0.284

Ā Ā 

0.613

ā€ƒYes

157 (43.4)

63 (48.8)

Ā 

66 (52.8)

62 (49.6)

Ā 

ā€ƒNo

205 (56.6)

66 (51.2)

Ā 

59 (47.2)

63 (50.4)

Ā 

Distance from anal verge (cm)

5.5 Ā± 1.4

5.1 Ā± 1.4

0.339

5.4 Ā± 1.5

5.1 Ā± 1.4

0.452

Histological type

Ā Ā 

0.025

Ā Ā 

0.172

ā€ƒWell/moderate

290 (80.1)

91 (70.5)

Ā 

81 (64.8)

91 (72.8)

Ā 

ā€ƒPoor/mucinous/signet

72 (19.9)

38 (29.5)

Ā 

44 (35.2)

34 (27.2)

Ā 

Pathological T stage

Ā Ā 

0.302

Ā Ā 

0.506

ā€ƒT1ā€“T2

71 (19.6)

20 (15.5)

Ā 

24 (19.2)

20 (16.0)

Ā 

ā€ƒT3ā€“T4

291 (80.4)

109 (84.5)

Ā 

101 (80.8)

105 (84)

Ā 

Mesorectal LN

Ā Ā 

<ā€‰0.001

Ā Ā 

0.855

ā€ƒN0

151 (41.7)

31 (24.0)

Ā 

25 (20.0)

28 (22.4)

Ā 

ā€ƒN1

149 (41.2)

60 (46.5)

Ā 

63 (50.4)

59 (47.2)

Ā 

ā€ƒN2

62 (17.1)

38 (30.4)

Ā 

37 (29.6)

38 (30.4)

Ā 

LPN metastasis

Ā Ā Ā Ā Ā 

ā€“

ā€ƒPresence

ā€“

26 (20.2)

Ā 

ā€“

25 (20.0)

Ā 

ā€ƒAbsence

ā€“

103 (79.8)

Ā 

ā€“

100 (80.0)

Ā 

Surgical approach

Ā Ā 

0.402

Ā Ā 

0.684

ā€ƒOpen

21 (5.8)

5 (3.9)

Ā 

2 (1.6)

4 (3.2)

Ā 

ā€ƒLaparoscopic

341 (94.2)

124 (96.1)

Ā 

123 (98.4)

121 (96.8)

Ā 

Lymphatic invasion

78 (21.5)

37 (28.7)

0.100

35 (28.0)

34 (27.2)

0.887

Perineural invasion

92 (25.4)

47 (36.4)

0.017

48 (38.4)

45 (36.0)

0.665

Adjuvant therapy

126 (34.8)

82 (63.6)

<ā€‰0.001

83 (66.4)

80 (64.0)

0.690