Table 5 Correlation of p53 and OCT1 expression with histological response in the CF group

Age (years)

≥ 65

30

22 (73.3)

8 (26.7)

0.722

< 65

17

14 (82.4)

3 (17.6)

Sex

Male

38

30 (78.9)

8 (21.1)

0.419

Female

9

6 (66.7)

3 (33.3)

Tumor location

Upper/middle

33

27 (81.8)

6 (18.2)

0.263

Lower/abdominal

14

9 (64.3)

5 (35.7)

Histological type

Well/moderate

37

30 (81.1)

7 (18.9)

0.213

Poor/basaloid

10

6 (60.0)

4 (40.0)

Clinical T factor

cT1/cT2

20

17 (85.0)

3 (15.0)

0.481

cT3/cT4

27

20 (74.1)

7 (25.9)

Clinical N factor

cN0

14

12 (85.7)

2 (14.3)

0.464

cN1/cN2/cN3

33

24 (72.7)

9 (27.3)

Clinical stage

II

18

15 (83.3)

3 (16.7)

0.492

III/IVa

29

21 (72.4)

8 (27.6)

p53 expression

Wild type

20

13 (65.0)

7 (35.0)

0.165

Mutant type

27

23 (85.2)

4 (14.8)

OCT1 expression

High

23

16 (69.6)

7 (30.4)

0.318

Low

24

20 (83.3)

4 (16.7)

p53/OCT1 expression

Both p53^WT-ex and OCT1^High

8

3 (37.5)

5 (62.5)

0.011*

Either p53^MT-ex or OCT1^Low

39

33 (84.6)

6 (15.4)