Skip to main content
Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: LINC00922 acts as a novel oncogene in gastric cancer

Fig. 5

MiR-204-5p targets HMGA2 in GC. A Three online databases (Targetscan 5.0, miRDB, and miRWalk 2.0) to predict common targets of miR-204-5p. B The levels of targets were measured by qRT-PCR assay in MKN-45, HGC-27, and GES-1. *P < 0.05, **P < 0.01, ***P < 0.001 vs. GES-1 group. C The potential binding sites of miR-204-5p with 3′UTR of HMGA2. D Luciferase reporter assay was used to assess the interaction between miR-204-5p and HMGA2. **P < 0.01 vs. NC mimic group, ## P < 0.01 vs. NC inhibitor group. E qRT-PCR and F western blot assays were used to assess HMGA2 level in MKN-45 and HGC-27 cells. **P < 0.01 vs. NC mimic group. G qRT-PCR was used to assess HMGA2 mRNA level in GC tissues 40 pairs of GC tissues and adjacent normal tissues. H Western blot assays were used to assess HMGA2 protein level in GC tissues. ***P < 0.001 vs. Normal group

Back to article page