Variable | Indicator | Univariate | Multivariate | |||
---|---|---|---|---|---|---|
p value | HR | 95% CI (range) | p value | |||
Age | ≥70 (vs <70) | 0.123 | ||||
Sex | Female (vs male) | 0.161 | ||||
HBV infection | Present (vs absent) | 0.214 | ||||
HCV infection | Present (vs absent) | 0.255 | ||||
Cirrhosis | Present (vs Absent) | 0.054 | 1.088 | 0.6123 | 1.935 | 0.773 |
Child-Pugh | B (vs A) | <0.001 | 1.019 | 0.3546 | 2.928 | 0.972 |
AFP (ng/ml) | ≥10 (vs <10) | 0.005 | 0.929 | 0.4952 | 1.743 | 0.819 |
AFP-L3 (%) | ≥10 (vs <10) | 0.028 | 1.595 | 0.8469 | 3.003 | 0.148 |
PIVKA-II (mAU/ml) | ≥40 (vs <40) | <0.001 | 1.645 | 0.9274 | 2.919 | 0.089 |
Tumor number | Multiple (vs aingle) | 0.022 | 1.206 | 0.7079 | 2.055 | 0.491 |
Tumor size (mm) | ≥50 (vs <50) | 0.006 | 0.7701 | 0.3534 | 1.678 | 0.511 |
LN metastasis | Present (vs absent) | <0.001 | 3.345 | 0.7132 | 15.69 | 0.126 |
Vascular invasions | Present (vs absent) | <0.001 | 2.125 | 1.234 | 3.659 | 0.007 |
Differentiation | Por/undif (vs well/mod) | 0.003 | 1.358 | 0.7725 | 2.388 | 0.288 |
Residual tumor | R1/2 (vs R0) | <0.001 | 5.986 | 2.366 | 15.14 | <0.001 |
Postoperative complications | ≥CD2 (vs ≤CD1) | 0.022 | 1.417 | 0.816 | 2.462 | 0.216 |
Blood transfusion | Present (vs absent) | <0.001 | 2.502 | 1.355 | 4.623 | 0.003 |