Table 2 Univariate and multivariate prognostic analysis for disease-specific survival among all patients

Age

≥70 (vs <70)

0.123

Sex

Female (vs male)

0.161

HBV infection

Present (vs absent)

0.214

HCV infection

Present (vs absent)

0.255

Cirrhosis

Present (vs Absent)

0.054

1.088

0.6123

1.935

0.773

Child-Pugh

B (vs A)

<0.001

1.019

0.3546

2.928

0.972

AFP (ng/ml)

≥10 (vs <10)

0.005

0.929

0.4952

1.743

0.819

AFP-L3 (%)

≥10 (vs <10)

0.028

1.595

0.8469

3.003

0.148

PIVKA-II (mAU/ml)

≥40 (vs <40)

<0.001

1.645

0.9274

2.919

0.089

Tumor number

Multiple (vs aingle)

0.022

1.206

0.7079

2.055

0.491

Tumor size (mm)

≥50 (vs <50)

0.006

0.7701

0.3534

1.678

0.511

LN metastasis

Present (vs absent)

<0.001

3.345

0.7132

15.69

0.126

Vascular invasions

Present (vs absent)

<0.001

2.125

1.234

3.659

0.007

Differentiation

Por/undif (vs well/mod)

0.003

1.358

0.7725

2.388

0.288

Residual tumor

R1/2 (vs R0)

<0.001

5.986

2.366

15.14

<0.001

Postoperative complications

≥CD2 (vs ≤CD1)

0.022

1.417

0.816

2.462

0.216

Blood transfusion

Present (vs absent)

<0.001

2.502

1.355

4.623

0.003