Table 1 Comparison of clinicopathological factors between L and S groups
Variable | S (<50 mm) n=360 (%) | L (≥50 mm) n=51 (%) | p value | |
|---|---|---|---|---|
Patient factors | ||||
Age | 71 [35–89] | 71 [16–85] | 0.964 | |
Sex | Male | 289 (79.8) | 42 (82.4) | 0.851 |
HBV infection | Present | 54 (15.0) | 11 (21.6) | 0.223 |
HCV infection | Present | 202 (56.1) | 13 (25.5) | <0.001 |
ICG-R15 (%) | 14.6 [3.2–49.7] | 13.3 [2.7–75.6] | 0.251 | |
Child-Pugh | B | 11 (3.1) | 2 (4.1) | 0.665 |
Tumor factors | ||||
AFP (ng/ml) | 6.8 [0.5–13310.0] | 11.0 [0.80–128900.0] | 0.009 | |
AFP-L3 (%) | 0.0 [0.0–99.5] | 7.2 [0.0–84.0] | 0.001 | |
PIVKA-II (mAU/ml) | 24.0 [8.0–17483.0] | 1011.0 [12.0–96988.0] | <0.001 | |
Tumor number | Multiple | 109 (30.1) | 15 (29.4) | 0.999 |
Vascular invasions | Present | 68 (18.9) | 26 (53.1) | <0.001 |
LN metastasis | Present | 2 (0.7) | 1 (2.0) | 0.397 |
Perioperative factors | ||||
Preoperative treatmenta | Present | 19 (5.2) | 14 (27.5) | <0.001 |
IBL (ml) | 531 [1–15759] | 828 [122–3330] | 0.003 | |
Operation time (min) | 375 [91–867] | 467 [257–791] | <0.001 | |
Blood transfusion | Present | 49 (13.6) | 13 (25.5) | 0.036 |
Residual tumor | R1/2 | 12 (3.3) | 5 (9.8) | 0.047 |
Postoperative complications | CD ≥2 | 120 (33.3) | 16 (31.4) | 0.874 |