Skip to main content

Table 2 GSEA analysis of B3GNT6 mRNA expression in GSE39582

From: Downregulation of B3GNT6 is a predictor of poor outcomes in patients with colorectal cancer

Geneset name

NES

NOM p-val

FDR q-val

BIOCARTA pathway

 Upregulated

  BIOCARTA_RAB_PATHWAY

1.6703635

0.026

0.33836955

  BIOCARTA_CERAMIDE_PATHWAY

1.6385397

0.03807615

0.34184185

 Downregulated

  BIOCARTA_PROTEASOME_PATHWAY

−1.865893

0.011235955

0.15191999

  KEGG pathway

 Upregulated

  KEGG_OLFACTORY_TRANSDUCTION

2.0274692

0

0.027611418

  KEGG_TASTE_TRANSDUCTION

1.7740936

0

0.19784024

  KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES

1.770417

0.001926782

0.13674085

  KEGG_O_GLYCAN_BIOSYNTHESIS

1.7251008

0.007736944

0.16378903

  KEGG_GNRH_SIGNALING_PATHWAY

1.7178557

0

0.14160849

  KEGG_ALZHEIMERS_DISEASE

1.6913323

0.026923077

0.15125382

  KEGG_NITROGEN_METABOLISM

1.6708751

0.001992032

0.13392551

  KEGG_LONG_TERM_POTENTIATION

1.64782

0.024528302

0.14832915

  KEGG_HUNTINGTONS_DISEASE

1.638019

0.04660194

0.14545798

  KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

1.63744

0.018072288

0.1325422

  KEGG_BUTANOATE_METABOLISM

1.6251645

0.01778656

0.13560429

  KEGG_DRUG_METABOLISM_OTHER_ENZYMES

1.6193944

0.01178782

0.13172121

  KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

1.5756354

0.025742574

0.17885368

  KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG

1.5706768

0.027613413

0.17375107

  KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS

1.5477382

0.046092186

0.19446045

  KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS

1.5473746

0.023391813

0.18385722

  KEGG_GLYCEROPHOSPHOLIPID_METABOLISM

1.5310374

0.015873017

0.1866673

  KEGG_RETINOL_METABOLISM

1.526893

0.02970297

0.18341947

  KEGG_GLYCOLYSIS_GLUCONEOGENESIS

1.5237751

0.038

0.17888556

  KEGG_VIBRIO_CHOLERAE_INFECTION

1.5188705

0.020876827

0.17640822

  KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION

1.4940959

0.048543688

0.20143263

  KEGG_STARCH_AND_SUCROSE_METABOLISM

1.4879901

0.037848607

0.20171466

  KEGG_ASCORBATE_AND_ALDARATE_METABOLISM

1.4647686

0.03976143

0.21592942

 Downregulated

  KEGG_BASAL_TRANSCRIPTION_FACTORS

−1.7745181

0.009920635

0.3991878

  KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS

−1.773844

0.013861386

0.20233367

  KEGG_RNA_DEGRADATION

−1.6950728

0.028688524

0.21618877

  KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE

−1.5696611

0.020715632

0.3765442

  KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE

−1.5518181

0.04183267

0.3753312

  1. NES normalized enrichment score, that is, the enrichment score for the gene set after it has been normalized across analyzed gene sets. FDR q-val false discovery rate, that is, the estimated probability that the normalized enrichment score represents a false positive finding. NOM p-val normalized p value, that is, the statistical significance of the enrichment score. The nominal p value is not adjusted for gene set size or multiple hypothesis testing; therefore, it is of limited use in comparing gene sets
Back to article page

World Journal of Surgical Oncology

ISSN: 1477-7819

Contact us