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Table 3 Results of univariable biniary and multivariable logistic regression analyses of variables with possible influence on 10% impairment of the postoperative eGFR

From: Impact of perioperative blood transfusions on postoperative renal function and survival after resection of colorectal liver metastases

Variables

Univariable binary logistic regression

Multivariable logistic regression

p value

OR (95%-CI)

p value

OR (95%-CI)

Preoperative variables

 Chemotherapy on primary tumor (Ref. yes)

0.992

1.003 (0.610–1.649)

Not included

 Development of CRLM (Ref. metachronous)

0.375

0.808 (0.504–1.295)

 Age at liver resection (years)

0.005

1.034 (1.010–1.058)

0.085

Not applicable

 Number of CRLM

0.590

1.029 (0.928–1.139)

Not included

 Size of CRLM

0.175

0.995 (0.987–1.002)

0.140

Not applicable

 Preoperative hemoglobin

0.858

0.987 (0.852–1.142)

Not included

 Preoperative platelets

0.548

1.001 (0.998–1.003)

 Preoperative quick

0.901

1.001 (0.984–1.018)

 Preoperative eGFR < 90 ml/min (Ref. normal values)

< 0.001

2.466 (1.502–4.050)

0.001

2.477 (1.478–4.151)

Intra- and postoperative variables

 Extent of liver resection (Ref. minor)

0.728

1.086 (0.682–1.729)

Not included

 Operative duration > 120 min (Ref. no)

0.116

1.003 (0.999–1.006)

0.548

Not applicable

 Use of Pringle maneuver (Ref. not used)

0.963

1.012 (0.614–1.668)

Not included

 Weight of liver specimen in g

0.529

1.000 (0.999–1.000)

 Overall transfusion of > 2 units PRBC (Ref. no)

0.051

1.586 (0.998–2.522)

0.046

1.638 (1.010–2.657)

 Postoperative complications graded Dindo-Clavien > 3 (Ref. no)

0.068

1.742 (0.961–3.157)

0.451

Not applicable

 ICU-stay (days)

0.298

1.017 (0.986–1.048)

0.790

  1. OR Odds ratio, CI Confidence intervall