Table 2 The frequencies of included variables in both the cohort with impaired and not affected renal function

 Female gender

31 (38.3%)

0 (0%)

254 (39.3%)

0 (0%)

0.856^a

 Male gender

50 (61.7%)

0 (0%)

392 (60.7%)

0 (0%)

 UICC I

6 (9.0%)

14 (17.3%)

51 (7.9%)

92 (14.2%)

0.901^b

 UICC IIa

14 (17.3%)

90 (13.9%)

 UICC IIb

0 (0%)

8 (1.2%)

 UICC IIc

0 (0%)

0 (0%)

 UICC IIIa

2 (2.5%)

17 (2.6%)

 UICC IIIb

7 (8.6%)

78 (12.1%)

 UICC IIIc

3 (3.7%)

24 (3.7%)

 UICC IV

35 (82.7%)

554 (85.8%)

 Chemotherapy of primary tumor

53 (65.4%)

2 (2.5%)

427 (66.1%)

9 (1.4%)

0.992^a

 Time to metastases (years)

1.27 (0–17)

4 (4.9%)

1.34 (0–14)

12 (1.9%)

0.785^c

 Synchronous metastases (%)

35 (43.2%)

2 (2.5%)

250 (38.7%)

7 (1.1%)

0.375^a

 Number of CRLM

2.5 (1–10)

1 (1.2%)

2.4 (1–11)

11 (1.7%)

0.590^c

 Age at liver resection (years)

65.3 (26–87)

0%

61.7 (24–90)

0%

0.005^c

 Platelets Tsd/μl (NR 160–370)

250 (96–794)

1 (1.2%)

244 (15–977)

4 (0.6%)

0.548^c

 Hemoglobin g/dl (NR 11.8–15.8)

13.4 (9.1–16.8)

0%

13.4 (8.2–18.3)

4 (0.6%)

0.857^c

 Quick % (NR 70–130)

99.3 (63–137)

1 (1.2%)

99.1 (10–145)

8 (1.2%)

0.904^c

 Preoperative eGFR (NR 90–130 ml/min)

84.9 (40.3–150.8)

0 (0%)

89.4 (4.9–130.2)

0 (0%)

0.022^c

 Preoperative eGFR < 90 ml/min

56 (69.1%)

307 (47.5%)

< 0.001^a

 Minor liver resection

45 (55.6%)

0 (0%)

372 (57.6%)

0 (0%)

0.728^a

 Major liver resection

36 (44.4%)

274 (42.4%)

 Operative duration in min

174 (40–385)

0 (0%)

163 (40–606)

4 (0.6%)

0.114^c

 Use of Pringle’s maneuver (in N cases)

25 (30.9%)

3 (3.7%)

201 (31.1%)

27 (4.2%)

0.963^a

 Pringle’s procedure in min if used

24.4 (7–72)

23.3 (4–63)

0.465^c

 Intraoperative transfusion of PRBC

1.7 (0–13)

0 (0%)

1.2 (0–42)

0 (0%)

0.125^c

 Postoperative transfusion of PRBC

1.2 (0–17)

0.8 (0–49)

0.266^c

 Overall transfusion of PRBC

2.9 (0–21)

2.0 (0–58)

0.089^c

 Size of largest metastasis in mm

44.7 (2–200)

3 (3.7%)

50.3 (4–220)

38 (5.9%)

0.175^c

 Weight of liver specimen in g

410 (2.2–2070)

3 (3.7%)

445 (2.8–4860)

34 (5.3%)

0.530^c

 Distance to resection margin in mm

4.4 (0–35)

5 (6.2%)

5.9 (0–70)

35 (5.4%)

0.139^c

 R-status R0

70 (86.4%)

1 (1.2%)

588 (91.0%)

8 (1.3%)

0.083^b

 R-status R1

9 (11.1%)

48 (7.4%)

 R-status R2

1 (1.2%)

2 (0.3%)

 eGFR at hospital dismission (Reference 90–130 ml/min)

64.5 (15.5–124-7)

0 (0%)

93.9 (6.5–138-7)

0 (0%)

< 0.001^c

 Dindo-Clavien classification of surgical complications grade 1

2 (2.5%)

0 (0%)

17 (2.6%)

0 (0%)

0.005^b

 Dindo-Clavien classification of surgical complications grade 2

17 (21.0%)

97 (15.0%)

 Dindo-Clavien classification of surgical complications grade 3

11 (13.6%)

67 (10.4%)

 Dindo-Clavien classification of surgical complications grade 4

6 (7.4%)

14 (2.2%)

 Complications graded Dindo-Clavien > 3

17 (21%)

81 (12.6%)

0.065^a