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Table 2 Univariate and multivariate Cox regression analysis of clinical factors and prognostic risk signature in the training cohort, the testing cohort and the entire cohort

From: Prediction of overall survival based upon a new ferroptosis-related gene signature in patients with clear cell renal cell carcinoma

Variable Training cohort Testing cohort Entire cohort
Univariate Multivariate Univariate Multivariate Univariate Multivariate
HR P HR P HR P HR P HR P HR P
Age: ≤ 65 vs. > 65 1.03 1.23e-03 1.04 1.10e-04 1.03 5.91e-03 1.04 9.28e-04 1.03 1.24e-05 1.04 2.98e-07
Gender: Female vs. Male 0.95 0.82 1.20 0.43 0.91 0.70 0.78 0.36 0.94 0.70 1.03 0.87
Grade: G1–2 vs. G3–4 2.05 7.1e-07 1.27 0.16 2.72 3.51e-09 1.67 7.49e-03 2.30 2.24e-14 1.31 3.09e-02
AJCC stage: I/II vs. III/IV 1.95 3.4e-13 1.75 0.08 1.91 3.42e-09 2.17 8.13e-03 1.93 9.60e-21 1.98 1.40e-03
T stage: T1–2 vs. T3–4 2.14 2.92e-11 1.00 0.99 1.80 1.35e-05 0.58 4.80e-02 1.99 3.80e-15 0.73 0.11
M stage: M0 vs. M1 4.07 1.76e-10 0.96 0.94 5.05 8.65e-11 1.38 0.50 4.39 2.68e-19 1.13 0.75
Risk score: Low vs. High 1.42 6.65e-12 1.46 5.13e-11 1.78 6.33e-08 1.68 4.14e-04 2.08 8.98e-22 2.04 6.91e-14