Fig. 4

Construction and evaluation of a prognostic signature based on seven FRGs in the training cohort. A Univariate Cox analysis reveals 11 candidate prognosis-related FRGs. B The optimal penalty parameter (λ) at the vertical line is selected following the minimum criteria (left). C Lasso coefficient profiles of the 11 candidates prognosis-related FRGs. D Kaplan–Meier curve shows that the high-risk group had significantly shorter OS than the low-risk group. E ROC curve demonstrates the veracity and reliability of the signature. F Risk score distribution of TCGA-ccRCC patients. G The distributions of risk scores and the survival status. H The heatmap displays that the expression levels of the seven FRGs in the high- and low-risk groups