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Table 3 Univariate analysis (log-rank test) for overall survival (n = 24)

From: Survival and prognostic factors in patients undergoing pulmonary metastasectomy for lung metastases from retroperitoneal sarcoma

Variables

n

3-year OS

95% CI

P value

Age (years)

   

< 0.001

 < 56

11

90.9%

50.8–98.7

 

 ≥ 56

13

38.5%

14.1–62.8

 

Sex

   

0.28

 Male

4

50.0%

5.8–84.5

 

 Female

20

65.0%

40.3–81.5

 

Histological subtypes

   

0.01

 Leiomyosarcoma

19

73.7%

47.9–88.1

 

 Dedifferentiated liposarcoma

3

NA

NA

 

 Others

2

NA

NA

 

Disease-free interval (months)

   

0.04

 < 15 months

9

44.4%

13.6–71.9

 

 ≥ 15 months

15

73.3%

43.6–89.1

 

Extent of lung metastases

   

0.2

 Unilateral

8

62.5%

22.9–86.1

 

 Bilateral

16

62.5%

34.9–81.1

 

Preoperative chemotherapy for lung metastases

   

0.84

 Yes

9

55.6%

20.4–80.5

 

 No

15

66.7%

37.5–84.6

 

NLR before the first PM

   

0.8

 < 1.92

6

83.3%

27.3–97.5

 

 ≥ 1.92

18

55.6%

30.5–74.8

 

NLR before the most recent PM

   

0.41

 < 2.48

15

60.0%

31.8–79.7

 

 ≥ 2.48

9

66.7%

28.2–87.8

 

Surgical approach

   

0.16

 Open

7

42.9%

9.8–73.4

 

 Mini-thoracotomy

13

69.2%

37.3–87.2

 

 VATS

4

75.0%

12.8–96.1

 

Type of resection

   

0.31

 Lobectomy

1

100.0%

NA

 

 Segmentectomy

6

50.0%

11.1–80.4

 

 Wedge resection

17

64.7%

37.7–82.3

 

Size of the largest resected tumor

   

0.04

 < 27mm

17

76.5%

48.8–90.4

 

 ≥ 27mm

7

28.6%

4.1–61.2

 

Total number of resected tumors

   

0.6

 < 7

13

61.5%

30.8–81.8

 

 ≥ 7

11

63.6%

29.7–84.5

 

Complete resection

   

0.17

 Yes

20

70.0%

45.1–85.3

 

 No

4

25.0%

0.9–66.5

 

Repeated resection

   

0.41

 Yes

15

66.7%

37.5–84.6

 

 No

9

55.6%

20.4–80.5

 
  1. RPS Retroperitoneal sarcoma, NLR Neutrophil-to-lymphocyte ratio, PM Pulmonary metastasectomy