Skip to main content
Fig. 5 | World Journal of Surgical Oncology

Fig. 5

From: Positive regulation of ataxia-telangiectasia-mutated protein (ATM) by E2F transcription Factor 1 (E2F-1) in cisplatin-resistant nasopharyngeal carcinoma cells

Fig. 5

Effect of E2F-1 on the proliferation of DDP-resistant NPC cells via regulation of ATM. Note: A, B EdU staining measured the effect of E2F-1 on the proliferation of DDP-resistant NPC cells via regulation of ATM (magnification, ×200, EdU staining in red, and DAPI staining in blue); C, D western blotting detected the protein expression of Ki67 in DDP-resistant NPC cells. The experiment was repeated independently three times. Comparisons among multiple groups were analyzed using one-way ANOVA, while intergroup differences were tested by Tukey’s HSD test. *, P < 0.05 compared with the blank group and control shRNA group; #, P < 0.05 compared with the E2F-1 shRNA#1 group and E2F-1 shRNA#2 group; &, P < 0.05 compared with the ATM group

Back to article page