| CSS | OS | ||
---|---|---|---|---|
Adjust HR (95% CI) | p value | Adjust HR (95% CI) | p value | |
Age | ||||
 < 50 | Reference |  |  |  |
 50–59 | 1.09 (0.94~1.25) | 0.247 | 1.13 (0.99~1.3) | 0.072 |
 60–69 | 1.21 (1.05~1.39) | 0.007 | 1.29 (1.13~1.48) | < 0.001 |
 70–79 | 1.35 (1.16~1.55) | < 0.001 | 1.54 (1.35~1.77) | < 0.001 |
 > 80 | 1.81 (1.55~2.11) | < 0.001 | 2.17 (1.87~2.5) | < 0.001 |
Gender | ||||
 Female | Reference |  |  |  |
 Male | 1.06 (0.97~1.16) | 0.203 | 1.06 (0.97~1.15) | 0.174 |
Race | ||||
 Black | Reference |  |  |  |
 White | 0.93 (0.81~1.06) | 0.275 | 0.88 (0.78~0.99) | 0.04 |
 Other | 0.73 (0.62~0.87) | < 0.001 | 0.68 (0.58~0.8) | < 0.001 |
Primary site | ||||
 Cardia, NOS | Reference |  |  |  |
 Fundus of stomach | 1.15 (0.89~1.49) | 0.294 | 1.04 (0.82~1.32) | 0.747 |
 Body of stomach | 1.07 (0.9~1.27) | 0.463 | 0.97 (0.83~1.14) | 0.732 |
 Gastric antrum | 1.07 (0.93~1.23) | 0.354 | 1.01 (0.89~1.15) | 0.851 |
 Pylorus | 1.06 (0.8~1.4) | 0.688 | 1.02 (0.79~1.32) | 0.889 |
 Lesser curvature of stomach, NOS | 0.92 (0.75~1.12) | 0.385 | 0.88 (0.73~1.05) | 0.156 |
 Greater curvature of stomach, NOS | 1.02 (0.8~1.3) | 0.862 | 0.96 (0.77~1.2) | 0.731 |
 Overlapping lesion of stomach | 1.24 (1.04~1.46) | 0.014 | 1.18 (1.01~1.38) | 0.041 |
 Stomach, NOS | 1.33 (1.14~1.54) | < 0.001 | 1.24 (1.08~1.43) | 0.002 |
Summary stage | ||||
 Unknown/unstaged | Reference |  |  |  |
 Distant | 3.04 (1.85~4.99) | < 0.001 | 2.46 (1.53~3.93) | < 0.001 |
 Localized | 1.42 (0.93~2.17) | 0.109 | 1.4 (0.95~2.06) | 0.094 |
 Regional | 2.29 (1.52~3.45) | < 0.001 | 1.95 (1.33~2.85) | 0.001 |
AJCC stage group | ||||
 Unknown stage | Reference |  |  |  |
 IA | 0.59 (0.39~0.88) | 0.009 | 0.65 (0.45~0.93) | 0.019 |
 IB | 0.82 (0.59~1.16) | 0.267 | 0.84 (0.61~1.16) | 0.295 |
 II | 0.66 (0.46~0.94) | 0.021 | 0.7 (0.5~0.97) | 0.034 |
 IIIA | 0.73 (0.51~1.05) | 0.087 | 0.78 (0.56~1.09) | 0.145 |
 IIIB | 1.27 (0.71~2.28) | 0.425 | 1.2 (0.67~2.13) | 0.536 |
 IV | 0.83 (0.58~1.2) | 0.326 | 0.88 (0.62~1.24) | 0.466 |
T stage | ||||
 T0 | Reference |  |  |  |
 T1 | 0.56 (0.08~4.02) | 0.56 | 0.55 (0.08~3.96) | 0.551 |
 T2a | 0.62 (0.09~4.48) | 0.635 | 0.62 (0.09~4.49) | 0.638 |
 T2b | 0.78 (0.11~5.6) | 0.805 | 0.74 (0.1~5.32) | 0.765 |
 T2NOS | 0.44 (0.06~3.42) | 0.43 | 0.42 (0.06~3.28) | 0.412 |
 T3 | 0.82 (0.11~5.88) | 0.842 | 0.79 (0.11~5.7) | 0.818 |
 T4 | 0.9 (0.13~6.45) | 0.915 | 0.85 (0.12~6.12) | 0.875 |
 TX | 0.83 (0.11~5.99) | 0.852 | 0.8 (0.11~5.75) | 0.82 |
N stage | ||||
 N0 | Reference |  |  |  |
 N1 | 1.09 (0.96~1.23) | 0.173 | 1.06 (0.95~1.2) | 0.307 |
 N2 | 1.01 (0.83~1.24) | 0.896 | 1.02 (0.84~1.24) | 0.866 |
 N3 | 1.33 (1.04~1.71) | 0.025 | 1.34 (1.05~1.7) | 0.017 |
 NX | 1.1 (0.9~1.35) | 0.363 | 1.1 (0.91~1.34) | 0.333 |
M stage | ||||
 M0 | Reference |  |  |  |
 M1 | 1.28 (0.92~1.77) | 0.139 | 1.31 (0.95~1.79) | 0.097 |
 MX | 0.94 (0.69~1.29) | 0.716 | 1.02 (0.77~1.35) | 0.892 |
Radiation | ||||
 No | Reference |  |  |  |
 Yes | 0.9 (0.79~1.02) | 0.087 | 0.89 (0.79~1) | 0.041 |
Chemotherapy | ||||
 No | Reference |  |  |  |
 Yes | 0.71 (0.63~0.81) | < 0.001 | 0.71 (0.63~0.8) | < 0.001 |
Systemic surgery | ||||
 No | Reference |  |  |  |
 Yes | 0.75 (0.64~0.87) | < 0.001 | 0.76 (0.66~0.88) | < 0.001 |
Marital | ||||
 No | Reference |  |  |  |
 Yes | 0.91 (0.81~1.01) | 0.089 | 0.88 (0.8~0.98) | 0.017 |
Surgery to primary site | ||||
 No | Reference |  |  |  |
 Yes | 0.35 (0.32~0.38) | <0.001 | 0.36 (0.33~0.39) | <0.001 |