Table 1 Demographic information for patients with signet ring cell carcinoma before PSM
| Â | All patients (n = 12483), n (%) | Non-surgery group (n = 6996), n (%) | Surgery group (n = 5487), n (%) | P |
|---|---|---|---|---|
Age | Â | Â | Â | < 0.001 |
 < 50 | 2457 (19.7) | 1373 (19.6) | 1084 (19.8) |  |
 50–59 | 2561 (20.5) | 1344 (19.2) | 1217 (22.2) |  |
 60–69 | 2916 (23.4) | 1528 (21.8) | 1388 (25.3) |  |
 70–79 | 2609 (20.9) | 1389 (19.9) | 1220 (22.2) |  |
 > 80 | 1940 (15.5) | 1362 (19.5) | 578 (10.5) |  |
Gender | Â | Â | Â | 0.312 |
 Female | 5989 (48.0) | 3328 (47.6) | 2661 (48.5) |  |
 Male | 6494 (52.0) | 3668 (52.4) | 2826 (51.5) |  |
Race | ||||
 Black | 1569 (12.6) | 898 (12.8) | 671 (12.2) |  |
 White | 8933 (71.6) | 5154 (73.7) | 3779 (68.9) |  |
 Other | 1981 (15.9) | 944 (13.5) | 1037 (18.9) |  |
Primary site | Â | Â | Â | < 0.001 |
 Cardia, NOS | 2207 (17.7) | 1417 (20.3) | 790 (14.4) |  |
 Fundus of stomach | 386 ( 3.1) | 251 (3.6) | 135 (2.5) |  |
 Body of stomach | 1487 (11.9) | 894 (12.8) | 593 (10.8) |  |
 Gastric antrum | 2688 (21.5) | 1180 (16.9) | 1508 (27.5) |  |
 Pylorus | 364 ( 2.9) | 131 (1.9) | 233 (4.2) |  |
 Lesser curvature of stomach, NOS | 1022 ( 8.2) | 362 (5.2) | 660 (12) |  |
 Greater curvature of stomach, NOS | 526 ( 4.2) | 228 (3.3) | 298 (5.4) |  |
 Overlapping lesion of stomach | 1332 (10.7) | 745 (10.6) | 587 (10.7) |  |
 Stomach, NOS | 2471 (19.8) | 1788 (25.6) | 683 (12.4) |  |
Summary stage | Â | Â | Â | < 0.001 |
 Unknown/unstaged | 968 ( 7.8) | 906 (13) | 62 (1.1) |  |
 Distant | 5267 (42.2) | 4330 (61.9) | 937 (17.1) |  |
 Localized | 2313 (18.5) | 924 (13.2) | 1389 (25.3) |  |
 Regional | 3935 (31.5) | 836 (11.9) | 3099 (56.5) |  |
AJCC stage group | Â | Â | Â | < 0.001 |
 Unknown stage | 1344 (10.8) | 1212 (17.3) | 132 (2.4) |  |
 IA | 1457 (11.7) | 590 (8.4) | 867 (15.8) |  |
 IB | 1059 ( 8.5) | 317 (4.5) | 742 (13.5) |  |
 II | 1280 (10.3) | 268 (3.8) | 1012 (18.4) |  |
 IIIA | 1149 ( 9.2) | 276 (3.9) | 873 (15.9) |  |
 IIIB | 360 ( 2.9) | 10 (0.1) | 350 (6.4) |  |
 IV | 5834 (46.7) | 4323 (61.8) | 1511 (27.5) |  |
T stage | Â | Â | Â | < 0.001 |
 T0 | 30 ( 0.2) | 29 (0.4) | 1 (0) |  |
 T1 | 2511 (20.1) | 1414 (20.2) | 1097 (20) |  |
 T2a | 858 ( 6.9) | 396 (5.7) | 462 (8.4) |  |
 T2b | 2320 (18.6) | 717 (10.2) | 1603 (29.2) |  |
 T2NOS | 94 ( 0.8) | 60 (0.9) | 34 (0.6) |  |
 T3 | 1942 (15.6) | 394 (5.6) | 1548 (28.2) |  |
 T4 | 1800 (14.4) | 1173 (16.8) | 627 (11.4) |  |
 TX | 2928 (23.5) | 2813 (40.2) | 115 (2.1) |  |
N stage | Â | Â | Â | < 0.001 |
 N0 | 5112 (41.0) | 3191 (45.6) | 1921 (35) |  |
 N1 | 3436 (27.5) | 1642 (23.5) | 1794 (32.7) |  |
 N2 | 1207 ( 9.7) | 120 (1.7) | 1087 (19.8) |  |
 N3 | 641 ( 5.1) | 72 (1) | 569 (10.4) |  |
 NX | 2087 (16.7) | 1971 (28.2) | 116 (2.1) |  |
M stage | Â | Â | Â | < 0.001 |
 M0 | 6689 (53.6) | 2146 (30.7) | 4543 (82.8) |  |
 M1 | 5022 (40.2) | 4174 (59.7) | 848 (15.5) |  |
 MX | 772 ( 6.2) | 676 (9.7) | 96 (1.7) |  |
Radiation | Â | Â | Â | < 0.001 |
 No | 9561 (76.6) | 5946 (85) | 3615 (65.9) |  |
 Yes | 2922 (23.4) | 1050 (15) | 1872 (34.1) |  |
Chemotherapy | Â | Â | Â | < 0.001 |
 No | 5922 (47.4) | 3493 (49.9) | 2429 (44.3) |  |
 Yes | 6561 (52.6) | 3503 (50.1) | 3058 (55.7) |  |
Systemic surgery | Â | Â | Â | < 0.001 |
 No | 9758 (78.2) | 6659 (95.2) | 3099 (56.5) |  |
 Yes | 2725 (21.8) | 337 (4.8) | 2388 (43.5) |  |
DX bone | Â | Â | Â | < 0.001 |
 No | 5457 (43.7) | 3015 (43.1) | 2442 (44.5) |  |
 Yes | 413 ( 3.3) | 398 (5.7) | 15 (0.3) |  |
 Unknown | 6613 (53.0) | 3583 (51.2) | 3030 (55.2) |  |
DX liver | Â | Â | Â | < 0.001 |
 No | 5495 (44.0) | 3056 (43.7) | 2439 (44.5) |  |
 Yes | 362 ( 2.9) | 338 (4.8) | 24 (0.4) |  |
 Unknown | 6626 (53.1) | 3602 (51.5) | 3024 (55.1) |  |
DX lung | Â | Â | Â | < 0.001 |
 No | 5576 (44.7) | 3131 (44.8) | 2445 (44.6) |  |
 Yes | 270 ( 2.2) | 254 (3.6) | 16 (0.3) |  |
 Unknown | 6637 (53.2) | 3611 (51.6) | 3026 (55.1) |  |
Resection range | Â | Â | Â | < 0.001 |
 No | 6996 (56.0) | 6996 (100) | 0 (0) |  |
 Local tumor resection | 114 ( 0.9) | 0 (0) | 114 (2.1) |  |
 Not-total gastrectomy surgery | 3436 (27.5) | 0 (0) | 3436 (62.6) |  |
 Total gastrectomy surgery | 1824 (14.6) | 0 (0) | 1824 (33.2) |  |
 Unknown | 113 ( 0.9) | 0 (0) | 113 (2.1) |  |
Year of diagnosis | Â | Â | Â | < 0.001 |
 2004–2007 | 4188 (33.5) | 2125 (30.4) | 2063 (37.6) |  |
 2008–2011 | 4075 (32.6) | 2265 (32.4) | 1810 (33) |  |
 2012–2015 | 4220 (33.8) | 2606 (37.2) | 1614 (29.4) |  |
Marital | Â | Â | Â | < 0.001 |
 No | 2667 (21.4) | 1651 (23.6) | 1016 (18.5) |  |
 Yes | 9816 (78.6) | 5345 (76.4) | 4471 (81.5) |  |