Table 2 Comparison of clinicopathologic characteristics between patients with and without VER
Variables | VER (n = 96) | Non-VER (n = 125) | P value |
|---|---|---|---|
Gender(male) | 79 (82.3%) | 108 (86.4%) | 0.515 |
Age (>= 65 years) | 15 (15.6%) | 24 (19.2%) | 0.608 |
Hepatitis | |||
 NBNC, n (%) | 12 (12.5%) | 18 (14.4%) | 0.668 |
 HBV, n (%) | 82 (85.4%) | 106 (84.8%) | |
 HCV, n (%) | 2 (2.1%) | 1 (0.8%) | |
 NAFLD, n (%) | 5 (5.2%) | 6 (4.8%) | 1 |
Cirrhosis (yes) | 65 (67.7%) | 84 (67.2%) | 1 |
Resection type (major resection) | 70 (72.9%) | 73 (58.4%) | 0.036 |
Lymph node dissection (yes) | 24 (25.0%) | 16 (12.8%) | 0.031 |
Tumor number (multiple) | 30 (31.3%) | 29 (23.2%) | 0.235 |
Tumor size (>= 5 cm) | 66 (68.8%) | 55 (44.0%) | < 0.001 |
Tumor capsule (present) | 52 (54.2%) | 72 (57.6%) | 0.709 |
Microvascular invasion (present) | 77 (80.2%) | 64 (51.2%) | < 0.001 |
Macrovascular invasion (present) | 38 (39.6%) | 16 (12.8%) | < 0.001 |
Satellite nodules (present) | 48 (50.0%) | 28 (22.4%) | < 0.001 |
Edmondson-Steiner classification (III/IV) | 21 (21.9%) | 26 (20.8%) | 0.978 |
RBC(>= 4 × 10^12/L) | 10 (10.4%) | 13 (10.4%) | 1 |
Hb(< 120*g/L) | 7 (7.3%) | 9 (7.2%) | 1 |
PLT(< 300 × 10^9/L) | 86 (89.6%) | 117 (93.6%) | 0.404 |
Neutrophil count(>= 5 × 10^9/L) | 63 (65.6%) | 97 (77.6%) | 0.068 |
Lymphocyte count(>= 1.5 × 10^9/L) | 23 (24.0%) | 32 (25.6%) | 0.902 |
NLR(> = 1.6) | 18 (18.8%) | 30 (24.0%) | 0.439 |
AST(>= 40 U/L) | 49 (51.0%) | 56 (44.8%) | 0.432 |
PT(>= 13 s) | 35 (36.5%) | 40 (32.0%) | 0.582 |
TB(>= 17.1 umol/L) | 22 (22.9%) | 34 (27.2%) | 0.569 |
ALB(< 40 g/L) | 33 (34.4%) | 48 (38.4%) | 0.635 |
GGT(>= 75 U/L) | 54 (56.3%) | 47 (37.6%) | 0.009 |
ALP(>= 78 U/L) | 77 (80.2%) | 72 (57.6%) | < 0.001 |
AFP(>= 20 ng/mL) | 72 (75.0%) | 72 (57.6%) | 0.011 |
CEA(>= 5 ng/mL) | 16 (16.7%) | 18 (14.4%) | 0.783 |
CA19-9(>= 25 U/mL) | 63 (65.6%) | 49 (39.2%) | < 0.001 |
DCP(>= 200 mAU/mL) | 41 (42.7%) | 32 (25.6%) | 0.011 |
Intraoperative blood loss(>= 200 mL) | 60 (62.5%) | 63 (50.4%) | 0.097 |
Intraoperative blood transfusion (yes) | 28 (29.2%) | 42 (33.6%) | 0.578 |