From: Clinical characteristics and patient outcomes of molecular subtypes of small cell lung cancer (SCLC)
Variables | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Gender | 1.523 | 0.489–4.746 | 0.468 |  |  |  |
Age | 0.284 | 0.064–1.250 | 0.096 |  |  |  |
Smoking status | 1.439 | 0.522–3.970 | 0.482 |  |  |  |
Tumor location | 1.313 | 0.492–3.499 | 0.587 |  |  |  |
Histology | 1.876 | 0.533–6.595 | 0.327 |  |  |  |
TNM stage | 4.021 | 1.471–10.994 | 0.007 | 0.035 | 0.001–2.419 | 0.121 |
T stage | 3.373 | 1.162–9.795 | 0.025 | 3.428 | 0.430–27.346 | 0.245 |
N stage | 3.467 | 1.244–9.664 | 0.017 | 31.714 | 1.543–652.031 | 0.025 |
Ki-67 status | 2.650 | 0.989–7.101 | 0.053 | 3.890 | 1.064–14.228 | 0.040 |
SCLC-A | 0.985 | 0.357–2.718 | 0.977 |  |  |  |
SCLC-N | 0.777 | 0.250–2.412 | 0.662 |  |  |  |
SCLC-P | 2.617 | 0.887–7.727 | 0.082 | 7.582 | 1.321–43.504 | 0.023 |
SCLC-I | 0.326 | 0.043–2.470 | 0.278 |  |  |  |
PD-L1 status | 0.226 | 0.030–1.716 | 0.151 |  |  |  |
CD8 status | 0.081 | 0.011–0.617 | 0.015 | 0.070 | 0.007–0.706 | 0.024 |
Adjuvant chemotherapy | 0.351 | 0.131–0.936 | 0.036 | 0.369 | 0.090–1.514 | 0.166 |
Adjuvant radiotherapy | 0.122 | 0.016–0.924 | 0.042 | 0.102 | 0.008–1.322 | 0.081 |