Characteristics | Progression-free survival | Overall survival | ||
---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Age (years) | Â | 0.380 | Â | Â |
 ≤ 65 | Reference |  |  |  |
 > 65 | 0.855 (0.602–1.213) |  |  |  |
Gender | Â | 0.606 | Â | Â |
 Female | Reference |  |  |  |
 Male | 1.096 (0.774–1.551) |  |  |  |
BMI (kg/m2) | Â | 0.599 | Â | 0.613 |
 BMI < 18.5 | Reference |  | Reference |  |
 18.5 ≤ BMI < 25 | 0.756 (0.345–1.658) | 0.486 | 0.836 (0.339–2.062) | 0.697 |
 BMI ≥ 25 | 0.680 (0.305–1.518) | 0.347 | 0.680 (0.251–1.799) | 0.428 |
Tumour location | Â | < 0.001 | Â | < 0.001 |
 Non-gastric | Reference |  | Reference |  |
 Gastric | 0.523 (0.372–0.736) |  | 0.409 (0.250–0.669) |  |
Tumour size (cm) | Â | 0.002 | Â | 0.018 |
 ≤ 10 | Reference |  | Reference |  |
 > 10 | 1.841 (1.255–2.700) |  | 1.889 (1.113–3.206) |  |
Mitotic index (per 50 HPF) | Â | 0.005 | Â | 0.115 |
 0–5 | Reference |  | Reference |  |
 6–10 | 0.891 (0.582–1.365) | 0.595 | 1.103 (0.609–1.995) | 0.747 |
 > 10 | 1.752 (1.186–2.589) | 0.005 | 1.749 (1.017–3.007) | 0.043 |
Surgical approach | Â | 0.209 | Â | 0.482 |
 Laparoscopy | Reference |  | Reference |  |
 Open | 1.413 (0.824–2.426) |  | 1.355 (0.581–3.159) |  |
Multi-organ involved | Â | 0.005 | Â | 0.173 |
 No | Reference |  | Reference |  |
 Yes | 1.868 (1.208–2.889) |  | 1.473 (0.844–2.570) |  |
Blood transfusion | Â | 0.865 | Â | 0.655 |
 No | Reference |  | Reference |  |
 Yes | 1.032 (0.721–1.476) |  | 1.118 (0.686–1.821) |  |
Postoperative imatinib | Â | < 0.001 | Â | < 0.001 |
 No | Reference |  | Reference |  |
 Yes | 0.493 (0.350–0.696) |  | 0.405 (0.246–0.669) |  |
NPS group | Â | < 0.001 | Â | < 0.001 |
 0 | Reference |  | Reference |  |
 1 | 4.622 (1.807–11.820) | 0.001 | 1.945 (0.668–5.660) | 0.222 |
 2 | 12.770 (4.932–33.059) | < 0.001 | 5.535 (1.923–15.929) | 0.002 |