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Table 1 Association of Naples prognostic score and clinicopathological characteristics

From: Naples prognostic score, a novel prognostic score for patients with high- and intermediate-risk gastrointestinal stromal tumours after surgical resection

Variables

Total n%

Naples prognostic score

P-value

Group 0 n%

Group 1 n%

Group 2 n%

All cases

405

46

204

155

 

Age (years)

    

0.677

 Mean ± SD

58.27 ± 10.75

58.17 ± 10.15

57.85 ± 10.72

58.86 ± 10.99

 

BMI (kg/m2)

    

0.639

 BMI < 18.5

16 (3.95)

0 (0.00)

8 (3.92)

8 (5.16)

 

 18.5 ≤ BMI < 25

225 (55.56)

26 (56.52)

114 (55.88)

85 (54.84)

 

 BMI ≥ 25

164 (40.49)

20 (43.48)

82 (40.20)

62 (40.00)

 

Gender

    

< 0.001

 Male

232 (57.28)

14 (30.43)

117 (57.35)

101 (65.16)

 

 Female

173 (42.72)

32 (69.57)

87 (42.65)

54 (34.84)

 

Tumour location

    

0.090

 Gastric

229 (56.54)

28 (60.87)

124 (60.78)

77 (49.68)

 

 Non-gastric

176 (43.46)

18 (39.13)

80 (39.22)

78 (50.32)

 

Tumour size

    

0.286

 Mean ± SD

9.291 ± 5.43

8.343 ± 4.02

9.172 ± 5.63

9.730 ± 5.51

 

Mitotic index (per 50 HPF)

    

0.496

 0–5

200 (49.38)

27 (58.70)

98 (48.04)

75 (48.39)

 

 6–10

107 (26.42)

12 (26.09)

57 (27.94)

38 (24.52)

 

 > 10

98 (24.20)

7 (15.22)

49 (24.02)

42 (27.10)

 

NIH risk category

    

0.177

 Intermediate

139 (34.32)

19 (41.30)

75 (36.76)

45 (29.03)

 

 High

266 (65.68)

27 (58.70)

129 (63.24)

110 (70.97)

 

Surgical approach

    

0.001

 Open

290 (71.60)

30 (65.22)

132 (64.71)

128 (82.58)

 

 Laparoscopy

115 (28.40)

16 (34.78)

72 (35.29)

27 (17.42)

 

Multi-organ involved

    

0.896

 Yes

51 (12.59)

6 (13.04)

27 (13.24)

18 (11.61)

 

 No

354 (87.41)

40 (86.96)

177 (86.76)

137 (88.39)

 

Blood transfusion

    

< 0.001

 Yes

115 (28.40)

6 (13.04)

45 (22.06)

64 (41.29)

 

 No

290 (71.60)

40 (86.96)

159 (77.94)

91 (58.71)

 

Complications

    

0.680

 Yes

182 (44.94)

18 (39.13)

92 (45.10)

72 (46.45)

 

 No

223 (55.06)

28 (60.87)

112 (54.90)

83 (53.55)

 

Hospitalization time (days)

    

0.054

 Mean ± SD

14.56 ± 5.82

13.22 ± 4.42

14.26 ± 5.29

15.35 ± 6.70

 

Postoperative imatinib

    

0.852

 Yes

183 (45.19)

20 (43.48)

95 (46.57)

68 (43.87)

 

 No

222 (54.81)

26 (56.52)

109 (53.43)

87 (56.13)

 
  1. Bold values indicate P < 0.05
  2. HPF high power field, SD standard deviation, IQR interquartile range, NIH National Institutes of Health