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Table 1 Demographic and clinical characteristics by body mass index (BMI) subgroups

From: The impact of body mass index (BMI) on MRI diagnostic performance and surgical management for axillary lymph node in breast cancer

  Total
N = 2084
Underweight
BMI < 18.50
N = 71
Normal
18.5 ≤ BMI < 24
N = 1045
Overweight
BMI ≥ 24
N = 968
p value
Age, years 53.4 ± 11.2 47.6 ± 11.6 51.4 ± 10.7 56.1 ± 11.1 < 0.01
Location      0.36
 Right 1006 (48.3) 38 (53.5) 515 (49.3) 453 (46.8)  
 Left 1078 (51.7) 33 (46.5) 530 (50.7) 515 (53.2)  
Tumor size on MRI, cm 3.4 ± 1.9 3.0 ± 1.6 3.2 ± 1.8 3.6 ± 1.9 < 0.01
Surgical method      0.52
 Total mastectomy 928 (44.5) 34 (47.9) 475 (45.5) 419 (43.3)  
 Partial mastectomy (BCS) 1156 (55.5) 37 (52.1) 570 (54.5) 549 (56.7)  
Specimen size, gm
 Total mastectomy 346.5 ± 200.1 153.7 ± 97.6 280.8 ± 140.8 466.9 ± 221.7 < 0.01
 Partial mastectomy (BCS) 62.7 ± 59.4 35 ± 22.8 53.1 ± 53.2 76.6 ± 65.6 < 0.01
Surgical ALN staging method      < 0.01
 SLNB 405 (19.4) 11 (15.5) 182 (17.4) 212 (21.9)  
 SLNB + ALND 1392 (66.8) 54 (76.1) 736 (70.4) 602 (62.2)  
 ALND 287 (13.8) 6 (8.5) 127 (12.2) 154 (15.9)  
Pathologic tumor size, cm 2.3 ± 1.6 2.0 ± 1.5 2.2 ± 1.6 2.4 ± 1.6 < 0.01
Pathologic stage      < 0.01
 I 856 (41.1) 37 (52.1) 485 (46.4) 334 (34.5)  
 II 1000 (48.0) 25 (35.2) 464 (44.4) 511 (52.8)  
 III 220 (10.6) 9 (12.7) 92 (8.8) 119 (12.3)  
 IV 8 (0.4) 0 4 (0.4) 4 (0.4)  
Histological type N/A = 63     0.73
 IDC 1822 (90.2) 65 (91.5) 921 (90.6) 836 (89.5)  
 ILC 97 (4.8) 3 (4.2) 50 (4.9) 44 (4.7)  
 Othersa 102 (5.0) 3 (4.2) 45 (4.4) 54 (5.8)  
Grade N/A = 42     0.50
 I 420 (20.6) 16 (23.2) 223 (21.7) 181 (19.1)  
 II 1137 (55.7) 34 (49.3) 562 (54.7) 541 (57.2)  
 III 485 (23.8) 19 (27.5) 242 (23.6) 224 (23.7)  
ER N/A = 10     0.71
 Positive 1714 (82.6) 61 (85.9) 856 (82.2) 797 (82.8)  
 Negative 360 (17.4) 10 (14.1) 185 (17.8) 165 (17.2)  
PR N/A = 9     0.77
 Positive 1533 (73.9) 55 (77.5) 767 (73.6) 711 (73.9)  
 Negative 542 (26.1) 16 (22.5) 275 (26.4) 251 (26.1)  
HER-2 N/A = 26     0.63
 Positive 403 (19.6) 17 (23.9) 199 (19.3) 187 (19.6)  
 Negative 1655 (80.4) 54 (76.1) 832 (80.7) 769 (80.4)  
Ki 67 N/A = 178     0.22
14 779 (40.9) 33 (48.5) 398 (41.9) 348 (39.2)  
 > 14 1127 (59.1) 35 (51.5) 553 (58.1) 539 (60.8)  
Molecular subtype N/A = 75     
 Luminal A 767 (38.2) 26 (39.4) 401 (39.9) 340 (36.2) 0.61
 Luminal B1 658 (32.8) 23 (34.8) 314 (31.2) 321 (34.2)  
 Luminal B2 266 (13.2) 9 (13.6) 128 (12.7) 129 (13.8)  
 HER-2(+) 151 (7.5) 6 (9.1) 78 (7.8) 67 (7.1)  
 TNBC 167 (8.3) 2 (3.0) 84 (8.4) 81 (8.6)  
  1. Statistically significant difference
  2. aOthers = metaplastic carcinoma, malignant phyllodes tumor, papillary carcinoma