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Table 3 Cases with appendiceal mucinous tumor and intussusception reported between January 2000 and February 2021

From: Multiple intestinal hemangioma concurrent with low-grade appendiceal mucinous neoplasm presenting as intussusception—a case report and literature review

Author Patient Presentation Histology Intussusception location Preoperative diagnosis study Treatment
Sex Age
Chua et al [1] F 30 Worsening right lower abdominal pain associated with nausea, vomiting, diarrhea LAMN pTis Ileocolic Intussusception CT Partial caecectomy with appendicectomy
Houlzé-Laroye [2] F 35 Abdominal symptoms evoking an intestinal obstruction LAMN pTis Ileo-caecal intussusception (ileo-caecal intussusception through the left transverse colon) CT Exploratory laparotomy and bowel resection
Nakamatsu et al [3] F 43 Right lower quadrant pain LAMN pTis Colonic intussusception located in the transverse colon Contrast-enhanced CT, biopsy colonoscopy Elective laparoscopy assisted ileocecal resection with lymph node dissection
Oliphant et al [4] F 20 Colicky central abdominal pain, vomiting, constipation LAMN pT3 Ileocolic Intussusception CT Extended right hemicolectomy
Coulier et al [5]   40 Intermittent right abdominal pain accompanied by a palpable mass in the right flank LAMN pTis Colo-colic intussusception with secondary ileocolic intussusception Helical CT, US Surgical reduction of the intussuscepting complex and ileo-cecal
Feliu et al [6] F 57 Intermittent and worsening abdominal pain, dizziness, diarrhea LAMN pTis Ileocolic intussusception X-ray, CT, laparoscopic Right hemicolectomy
Cois et al [7] F 36 Colicky pain located in the central abdomen, radiating to the flanks and associated with nausea LAMN pTis Right colonic intussusception CT, US Laparotomy, partial resection of the caecum and right ovary
Yamaguchi et al [8] F 32 Intermittent abdominal pain and nonbloody diarrhea LAMN pTis Colic intussusception X-ray, CT, colonoscopy, biopsy, barium enema Laparoscopic reduction of intussusception and ileocecal resection
Rudek et al [9] M 52 acute right lower abdominal pain LAMN pTis Appendix was partially intussuscepted into the cecum Plain X-rays, US, CT Ileocecal resection with regional lymphadenectomy, ileocolic anastomosis
Sun et al [10] F 57 Hematochezia, changes in defecation habits, mild swelling and pain in the right lower quadrant of abdomen LAMN pTis and rectal medium-low differentiated adenocarcinoma (cT4N1M0) Appendix intussuscepted into the Cecum CT, colonoscopy, biopsy Resection of both the appendix and ileocecum, radical resection of the rectal Carcinoma, regular chemotherapy for rectal carcinoma
Okuda et al [11] M 44 Asymptomatic LAMN pTis Ileocolic intussusception US, reconstructed CT images, coronal and sagittal multiplanar reconstruction (MPR) images, MRI Laparoscopic ileocecectomy
Lin et al [12] M 28 Diffuse abdominal pain but more localized over the epigastric area and right lower quadrant with McBurney point tenderness LAMN pT4a Ileocolic intussusception CT scan Right hemicolectomy
Butte et al [13] F 41 Episodic abdominal pain, abdominal distention and nausea HAMN and well-differentiated neuroendocrine carcinoma Distal ileum and appendix intussuscepted into the cecum US, colonoscopy, CT, Biopsies Right colectomy
Waseem et al [14] F 84 Caecum intussuscepting into the transverse colon along with the appendix and ileum LAMN pTis Caecum intussuscepting into the transverse colon along with the appendix and ileum ileocaeco-colic intussusception Plain radiographs, US forceful reduction, Right hemicolectomy and ileocolic anastomosis
Teke et al [15] F 37 Acute onset, right lower abdominal pain LAMN pTis Appendix intussuscepting into the caecum CT Ileocaecal resection
Laalim et al [16] F 47 pain in the right side of the abdomen, nausea and vomiting LAMN pTis Appendiceal intussusception to the cecum and secondary distal ileum invagination US, CT Laparoscopic right hemicolectomy
Davey MG et al [17] M 42 Sudden onset abdominal pain and bloody diarrhea LAMN pTis ileocecal intussusception at the hepatic flexure Endoscopy, CT Right hemicolectomy
Ashrafifi M et al [18] M 35 Abdominal pain and an altered bowel habit., diarrhea, vomiting, and abdominal distension, anorexia LAMN pT4a Appendiceal intussusception to the cecum Digital rectal examination and rigid sigmoidoscopy Colonoscopy, Biopsies, CT colonography Appendicectomy, partial caecectomy
Blondiaux E et al [19] F 63 Right lower quadrant abdominal pain Simple retention cysts Dilated proximal portion of the appendix intussuscepted in the cecum lumen CT Right hemi-colectomy
Siddiqi AJ et al [20] F 22 Acute right lower quadrant pain LAMN pTis Ileocolic intussusception with an appendiceal mucocele serving as the lead point Multidetector CT scan of the abdomen and pelvis Appendectomy and ileocecal resection
Wong MT et al [21] F 81 Intermittent right-sided abdominal pain Simple retention cysts and Schistosomiasis colonic intussusception Digital rectal examination, plain abdominal radiographs, CT Right hemicolectomy
Chan Ket et al [22] F 41 Intermittent, right-sided abdominal pain, abdominal distension, nausea, and vomiting LAMN pTis Ileocolic intussusception CT, Colonoscopy Laparoscopic right hemicolectomy
Birkness J et al [23] F 46 LAMN pTis Appendiceal intussusception Colonoscopy Right colon resection
Birkness J et al [23] F 64 LAMN pTis Appendiceal intussusception Colonoscopy Cecal resection
Birkness J et al [23] F 47 Serrated dysplasia, Low grade Appendiceal intussusception Colonoscopy Right colon resection
  1. US ultrasound, CT computer tomography, − data not available, MRI magnetic resonance imaging, MRA magnetic resonance angiography, LAMN low-grade appendiceal mucinous neoplasms, HAMN high-grade appendiceal mucinous neoplasm
  2. LAMN pTis: LAMN confined to the muscularis propria (defined as involvement by acellular mucin or mucinous epithelium that may extend into muscularis propria)
  3. LAMN pT3: LAMNs invades subserosa or mesoappendix
  4. LAMN pT4a: LAMNs perforates visceral peritoneum, including mucinous peritoneal tumor or acellular mucin on the serosa of the appendix or mesoappendix
  5. LAMN pT4b: LAMNs directly invades other organs or structures