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Table 2 Cases diagnosed with intestinal hemangioma and intussusception reported between January 2000 and February 2021

From: Multiple intestinal hemangioma concurrent with low-grade appendiceal mucinous neoplasm presenting as intussusception—a case report and literature review

Author Patient Presentations Hemangioma location Histology Intussusception location Preoperative diagnosis Treatment
Sex Age, year
Wang et al [1] M 19 BRBNS with melena and abdominal pain Jejunum and gastric lumen Cavernous hemangiomas Jejunojejunal intussusception CT Exploratory, laparotomy, intraoperative esophagogastroduodenoscopy, wedge gastrectomy and a part of jejunum were resected
Menegozzo et al [2] F 25 Chronic intestinal bleeding presented with acute onset of colic pain and vomit Small and large bowels, Liver Cavernous hemangiomas Jejunum US, CT Laparotomy, simple reduction of the intussusception segments
Tzoufi et al [3] M 13 Complex partial generalized seizures, cerebral palsy, multiple skeletal anomalies anaemia Skins, mucous membranes, gastrointestinal tract, left occipital lobe Cavernous hemangiomas Ileocolic intussusception CT, MRI Surgery, blood transfusions
Lee et al [4] M 37 Colicky abdominal pain, nausea, vomiting Jejunum, mid-ileum and distal ileum, Bluish skin lesions around neck, chest and abdomen, hepatic, right quadratus lumborum muscle Cavernous hemangiomas Jejunum, mid-ileum and distal ileum Abdominal radiograph, CT Urgent laparotomy and bowel resections, limited right hemicolectomy
Keiko et al [5] M 2 years and 10 months Vomiting, diarrhea, abdominal pain, watery diarrhea with strawberry jelly-like stools Cecum Capillary Colon US, CT, colonoscopy, barium enema laparotomy with ileocecal resection and side to-end ileo-ascending colon anastomosis
Khalil et al [6] F 17 Abdominal pain, lower gastrointestinal bleeding and anaemia Rectosigmoid, hepatic flexure, small bowel Multiple cavernous haemangioma Small bowel Colonoscopy, nuclear medicine GI bleeding scintigraphic scanning, CT angiogram Surgical exploration, Enterotomy small bowel resection, colotomy, ligation and excision of the hepatic flexure and rectosigmoid region
Zorica et al [7] F 13 Vomiting, colicky abdominal pain and constipation. Ileal Pyogenic granuloma, lobular capillary hemangioma ileum US, Plain abdominal radiography Laparotomy. The affected gangrenous loop of the small bowel was resected and a temporary terminal ileostomy was performed
Morgan et al [8] F 21 Abdominal pain and vomiting Small bowel, lymph nodes Mixed haemangioma mid small bowel US, CT, Gastrography enema Laparotomy. The affected loop of small bowel was resected, together with the mass and the lymph nodes, and an end to end anastomosis was performed
Kye et al [9] F 81 Intermittent melena, nausea, dizziness, severe anemia Jejunum Polypoid hemangioma of a proliferation of dilated vessels and small capillaries Jejunum CT, esophagogastroduodenoscopy colonoscopy (EGD), colonoscopic Explorative laparotomy, segmental resection of the small bowel
Al-Musali B et al [10] F 0.25 Projectile vomiting, abdominal pain, and redcurrant jelly stool Ilium Diffuse infantile hemangioma Not available Laparoscopy, US, CT, MRI, MRA Surgical resection of the thickened circumferential hemangioma covering the mid ilium along with oral propranolol
  1. US ultrasound, CT computer tomography, MRI magnetic resonance imaging, MRA magnetic resonance angiography