Table 6 Significant factors affecting overall survival within 2 years by univariable and multivariable Cox proportional hazard model regression analysis

Karnofsky performance status

0.955 (0.924–0.988)

0.007

0.959 (0.916–1.003)

0.070

ECOG performance status ≥ 1

2.715 (1.117–6.601)

0.028

2.849 (0.908–8.936)

0.073

National ADI≥ 90 based on index encounter address

3.266 (1.136–9.388)

0.028

0.374 (0.049–2.834)

0.341

Low socioeconomic status

2.477 (1.009–6.079)

0.048

1.131 (0.397–3.225)

0.818

pTNM stage IV

3.801 (1.441–10.026)

0.007

3.292 (1.042–10.408)

0.042*

Clavien-Dindo minor complications

2.254 (1.120–4.538)

0.023

2.063 (0.958–4.442)

0.064

Locoregional recurrence

2.029 (0.876–4.699)

0.099

1.244 (0.442–3.501)

0.679

Distant recurrence

5.430 (2.659–11.089)

< 0.001*

5.784 (2.612–12.810)

<0.001*