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Table 5 Factors affecting overall survival by univariable and multivariable Cox proportional hazard model regression analysis in 96 patients

From: Long-term survival outcomes of esophageal cancer after minimally invasive Ivor Lewis esophagectomy

  Univariable   Multivariable  
Unadjusted HR (95% CI) p-value Adjusted HR (95% CI) p-value
Age 1.049 (1.006–1.093) 0.023 1.060 (1.009–1.114) 0.022*
ASA 4 7.801 (1.751–34.748) 0.007 0.676 (0.099–4.623) 0.690
White blood cell count 1.241 (1.066–1.445) 0.005 1.203 (0.981–1.427) 0.078
Karnofsky performance status 0.959 (0.929–0.991) 0.011 0.937 (0.900–0.976) 0.002*
Low socioeconomic status 2.590 (1.130–5.933) 0.024 1.410 (0.481–4.134) 0.531
pTNM stage IV 4.633 (1.883–11.400) 0.001 5.615 (1.869–16.872) 0.002*
Presence of lymphovascular invasion 2.040 (1.038–4.010) 0.04 0.727 (0.270–1.961) 0.529
Clavien-Dindo minor complications 2.308 (1.229–4.332) 0.009 0.695 (0.278–1.737) 0.437
Locoregional recurrence 2.256 (1.071–4.752) 0.032 2.943 (1.129–7.670) 0.027*
Distant recurrence 6.534 (3.381–2.626) < 0.001 4.784 (2.102–10.889) < 0.001*
  1. HR, hazard ratio; CI, confidence interval; pTNM, pathological tumor-node-metastasis stage; ASA, American Society of Anaesthesiologists physical status score. Only significant variables on univariable analysis incorporated into multivariable model and summarized in the table. *Statistically significant values (p < 0.05)