Table 5 Factors affecting overall survival by univariable and multivariable Cox proportional hazard model regression analysis in 96 patients

Age

1.049 (1.006–1.093)

0.023

1.060 (1.009–1.114)

0.022*

ASA 4

7.801 (1.751–34.748)

0.007

0.676 (0.099–4.623)

0.690

White blood cell count

1.241 (1.066–1.445)

0.005

1.203 (0.981–1.427)

0.078

Karnofsky performance status

0.959 (0.929–0.991)

0.011

0.937 (0.900–0.976)

0.002*

Low socioeconomic status

2.590 (1.130–5.933)

0.024

1.410 (0.481–4.134)

0.531

pTNM stage IV

4.633 (1.883–11.400)

0.001

5.615 (1.869–16.872)

0.002*

Presence of lymphovascular invasion

2.040 (1.038–4.010)

0.04

0.727 (0.270–1.961)

0.529

Clavien-Dindo minor complications

2.308 (1.229–4.332)

0.009

0.695 (0.278–1.737)

0.437

Locoregional recurrence

2.256 (1.071–4.752)

0.032

2.943 (1.129–7.670)

0.027*

Distant recurrence

6.534 (3.381–2.626)

< 0.001

4.784 (2.102–10.889)

< 0.001*