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Table 1 Baseline characteristics of CRC patients in our study

From: Nomogram for predicting occurrence of synchronous liver metastasis in colorectal cancer: a single-center retrospective study based on pathological factors

Characteristics Development cohort (n, %) Validation cohort (n, %) P value
Age (years)    0.923
 < 60 645 (40.4) 644 (40.4)  
 60–74 737 (46.2) 745 (46.7)  
 ≥ 75 213 (13.4) 206 (12.9)  
BMI    0.273
 < 25 1123 (70.4) 1151 (72.2)  
 ≥ 25 472 (29.6) 444 (27.8)  
Sex    0.054
 Male 1011 (63.4) 958 (60.1)  
 Female 584 (36.6) 637 (39.9)  
Tumor site    0.663
 Right-sited colon 353 (22.1) 373 (23.4)  
 Left-sited colon 376 (23.6) 373 (23.4)  
 Rectum 866 (54.3) 849 (53.2)  
Tumor size (cm)    0.187
 ≤ 5 915 (57.4) 878 (55.0)  
 > 5 680 (42.6) 717 (45.5)  
Tumor type    0.671
 Ulcer type* 1152 (72.2) 1170 (73.4)  
 Uplift type* 430 (27.0) 415 (26.0)  
 Infiltrating type* 13 (0.8) 10 (0.6)  
Grade    0.678
 I/II 1376 (86.3) 1384 (86.8)  
 III/IV 219 (13.7) 211 (13.2)  
Histology    
 Adenocarcinoma 1288 (80.8) 1270 (79.6) 0.726
 Mucinous 290 (18.2) 307 (19.2)  
 Other 17 (1.1) 18 (1.1)  
T    0.128
 T1/T2 172 (10.8) 166 (10.4)  
 T3 703 (44.1) 653 (40.9)  
 T4 720 (45.1) 776 (48.7)  
N    0.839
 N0 1009 (63.3) 1014 (63.6)  
 N1 372 (23.3) 378 (23.7)  
 N2 214 (13.4) 203 (12.7)  
LNE    
 < 12 262 (16.4) 274 (17.2)  
 ≥ 12 1333 (83.6) 1321 (82.8)  
Vascular invasion    0.295
 No 1135 (71.2) 1108 (69.5)  
 Yes 460 (28.8) 487 (30.5)  
Nerve invasion    0.667
 No 682 (42.8) 670 (42.0)  
 Yes 913 (57.2) 925 (58.0)  
Lymphatic invasion    0.499
 No 1071 (67.1) 1053 (66.0)  
 Yes 524 (32.9) 542 (34.0)  
CEA    0.472
 Positive 504 (31.6) 523 (32.8)  
 Negative 1091 (68.4) 1072 (67.2)  
CA199    0.516
 Positive 241 (15.1) 228 (14.3)  
 Negative 1354 (84.9) 1367 (85.7)  
Liver metastasis    0.831
 Yes 104 (6.5) 107 (6.7)  
 No 1491 (93.5) 1488 (93.3)  
  1. Ulcer type*: the tumor grew into the intestinal lumen. Uplift type*: the tumor is infiltrating around the intestinal wall. Infiltrating type*: tumors grow deep into the intestinal wall and invade outwards and appears to be marginal and deep at the bottom