Table 1 Baseline characteristics of CRC patients in our study
Characteristics | Development cohort (n, %) | Validation cohort (n, %) | P value |
|---|---|---|---|
Age (years) | Â | Â | 0.923 |
 < 60 | 645 (40.4) | 644 (40.4) |  |
 60–74 | 737 (46.2) | 745 (46.7) |  |
 ≥ 75 | 213 (13.4) | 206 (12.9) |  |
BMI | Â | Â | 0.273 |
 < 25 | 1123 (70.4) | 1151 (72.2) |  |
 ≥ 25 | 472 (29.6) | 444 (27.8) |  |
Sex | Â | Â | 0.054 |
 Male | 1011 (63.4) | 958 (60.1) |  |
 Female | 584 (36.6) | 637 (39.9) |  |
Tumor site | Â | Â | 0.663 |
 Right-sited colon | 353 (22.1) | 373 (23.4) |  |
 Left-sited colon | 376 (23.6) | 373 (23.4) |  |
 Rectum | 866 (54.3) | 849 (53.2) |  |
Tumor size (cm) | Â | Â | 0.187 |
 ≤ 5 | 915 (57.4) | 878 (55.0) |  |
 > 5 | 680 (42.6) | 717 (45.5) |  |
Tumor type | Â | Â | 0.671 |
 Ulcer type* | 1152 (72.2) | 1170 (73.4) |  |
 Uplift type* | 430 (27.0) | 415 (26.0) |  |
 Infiltrating type* | 13 (0.8) | 10 (0.6) |  |
Grade | Â | Â | 0.678 |
 I/II | 1376 (86.3) | 1384 (86.8) |  |
 III/IV | 219 (13.7) | 211 (13.2) |  |
Histology | Â | Â | Â |
 Adenocarcinoma | 1288 (80.8) | 1270 (79.6) | 0.726 |
 Mucinous | 290 (18.2) | 307 (19.2) |  |
 Other | 17 (1.1) | 18 (1.1) |  |
T | Â | Â | 0.128 |
 T1/T2 | 172 (10.8) | 166 (10.4) |  |
 T3 | 703 (44.1) | 653 (40.9) |  |
 T4 | 720 (45.1) | 776 (48.7) |  |
N | Â | Â | 0.839 |
 N0 | 1009 (63.3) | 1014 (63.6) |  |
 N1 | 372 (23.3) | 378 (23.7) |  |
 N2 | 214 (13.4) | 203 (12.7) |  |
LNE | Â | Â | Â |
 < 12 | 262 (16.4) | 274 (17.2) |  |
 ≥ 12 | 1333 (83.6) | 1321 (82.8) |  |
Vascular invasion | Â | Â | 0.295 |
 No | 1135 (71.2) | 1108 (69.5) |  |
 Yes | 460 (28.8) | 487 (30.5) |  |
Nerve invasion | Â | Â | 0.667 |
 No | 682 (42.8) | 670 (42.0) |  |
 Yes | 913 (57.2) | 925 (58.0) |  |
Lymphatic invasion | Â | Â | 0.499 |
 No | 1071 (67.1) | 1053 (66.0) |  |
 Yes | 524 (32.9) | 542 (34.0) |  |
CEA | Â | Â | 0.472 |
 Positive | 504 (31.6) | 523 (32.8) |  |
 Negative | 1091 (68.4) | 1072 (67.2) |  |
CA199 | Â | Â | 0.516 |
 Positive | 241 (15.1) | 228 (14.3) |  |
 Negative | 1354 (84.9) | 1367 (85.7) |  |
Liver metastasis | Â | Â | 0.831 |
 Yes | 104 (6.5) | 107 (6.7) |  |
 No | 1491 (93.5) | 1488 (93.3) |  |