Parameters | Univarite analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Hazard ratio | 95% CI | p value | Hazard ratio | 95% CI | p value | |
Age at operation (years) | ||||||
 ≤ 45 vs > 60 | 0.916 | 0.651–1.300 | 0.619 |  |  |  |
Tumor size (mm) | ||||||
 ≤ 20 vs > 20 | 0.674 | 0.309–1.684 | 0.373 |  |  |  |
Skin infiltration | ||||||
 Negative vs positive | 2.629 | 1.140–5.582 | 0.025 | 2.597 | 1.075–5.858 | 0.035 |
Lymph node status | ||||||
 Negative vs positive | 4.935 | 1.756–20.600 | 0.001 | 3.981 | 1.385–16.828 | 0.008 |
Estrogen receptor | ||||||
 Negative vs positive | 0.738 | 0.358–1.469 | 0.390 |  |  |  |
Progesterone receptor | ||||||
 Negative vs positive | 0.733 | 0.322–1.524 | 0.418 |  |  |  |
Hormone receptor | ||||||
 Negative vs positive | 0.675 | 0.327–1.344 | 0.265 |  |  |  |
HER2 | ||||||
 Negative vs positive | 0.237 | 0.070–0.602 | 0.001 | 0.479 | 0.130–1.423 | 0.193 |
Intrinsic subtype | ||||||
 Not TNBC vs TNBC | 2.710 | 1.356–5.392 | 0.005 | 2.418 | 1.080–5.456 | 0.032 |
Ki67 | ||||||
 ≤ 14% vs > 14% | 2.339 | 1.066–5.872 | 0.033 | 2.489 | 1.089–6.417 | 0.030 |
Objective response rate | ||||||
 Non-responders vs responders | 0.309 | 0.145–0.734 | 0.010 | 0.381 | 0.159–0.984 | 0.047 |
Pathological response | ||||||
 Non-pCR vs pCR | 0.195 | 0.058–0.499 | < 0.001 | 0.238 | 0.065–0.685 | 0.006 |
TILs | ||||||
 Low vs high | 0.523 | 0.253–1.045 | 0.066 | 0.991 | 0.431–2.231 | 0.982 |