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Table 2 Cox multivariate regression analysis of disease-free survival, cancer-specific survival, and overall survival correlation of tumor deposits

From: Association of tumor deposits with tumor-infiltrating lymphocytes and prognosis in gastric cancer

  DFS   CSS   OS  
HR (95% CI) P-value HR (95% CI) P-value HR (95% CI) P-value
TDs 0.571 (0.353–0.923) 0.022 0.464 (0.302–0.713) 0.000 0.538 (0.356–0.814) 0.003
Age, years 0.638 (1.089–2.462) 0.018
Histologic grade 1.040 (0.444–2.433) 0.929 1.198 (0.540–2.659) 0.657
Lauren classification   0.610   0.446
 Lauren (1)    0.668 (0.268–1.663) 0.385 0.579 (0.248– 0.207
 Lauren (2)    0.863 (0.311–2.399) 0.778 1.354)
0.688 (0.264–1.792)
0.444
LVI 0.549 (0.207–1.454) 0.228 0.960 (0.392–2.348) 0.929 0.940 (0.404–2.184) 0.885
PNI 0.511 (0.259–1.009) 0.053 0.599 (0.324–1.105) 0.101 0.685 (0.387–1.214) 0.195
pT stage   0.353   0.019   0.009
 T(1) 0.703 (0.119–4.158) 0.698 0.290 (0.021–3.940) 0.352 1.023 (0.162–6.454) 0.981
 T(2) 0.641 (0.091–4.519) 0.655 2.000 (0.134–29.774) 0.615 2.879 (0.312–26.583) 0.351
 T(3) 1.070 (0.144–7.925) 0.947 4.142 (0.269–63.863) 0.309 6.655 (0.700–63.284) 0.099
pN stage   0.590   0.126   0.078
 N(1) 0.921 (0.274–3.101) 0.895 1.439 (0.406–5.106) 0.573 1.312 (0.404–4.262) 0.651
 N(2) 0.589 (0.137–2.523) 0.476 1.120 (0.241–5.205) 0.885 1.025 (0.246–4.270) 0.973
 N(3) 0.847 (0.200–3.586) 0.822 2.117 (0.476–9.409) 0.325 2.022 (0.506–8.075) 0.319
Clinical stage   0.563   0.442   0.299
 Clinical stage (1) 2.258 (0.297–17.150) 0.431 0.608 (0.037–9.896) 0.727 0.492 (0.058–4.183) 0.516
 Clinical stage (2) 4.746 (0.335–67.150) 0.249 1.029 (0.037–28.548) 0.986 0.775 (0.054–11.212) 0.852
 Clinical stage (3) 2.698 (0.095–76.460) 0.561 1.901 (0.060–60.743) 0.716 1.559 (0.092–26.538) 0.759
  1. LVI, lymphovascular invasion; PNI, perineural invasion; TDs, tumor deposits