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Table 5 Day-to-day intra-individual variability Indices of CRP, PCT, and WBC for anastomotic leakage

From: Role of the triad of procalcitonin, C-reactive protein, and white blood cell count in the prediction of anastomotic leak following colorectal resections

Within table-individual variability

No AL

AL

Mean difference (95% CI)

p value

CRP

SD

30.72 (24.9)

74.67 (33.8)

43.9 (32.4–55.5)

< 0.001*

CV

0.68 (0.22)

0.93 (0.14)

0.25 (0.16–0.35)

< 0.001*

VIM

31.90 (9.78)

41.45 (8.25)

9.56 (5.27–13.8)

< 0.001*

PCT

SD

0.66 (0.45)

2.27 (1.09)

1.61 (1.12–2.10)

< 0.001*

CV

0.47 (0.14)

0.71 (0.21)

0.24 (0.14–0.33)

< 0.001*

VIM

0.87 (0.37)

0.85 (0.27)

− 0.02 (− 0.18–0.15)

0.673

WBC

SD

1.25 (1.55)

1.92 (0.60)

0.67 (0.01–1.33)

< 0.001*

CV

0.17 (0.13)

0.24 (0.06)

0.08 (0.02–0.13)

< 0.001*

VIM

1.67 (2.19)

1.63 (0.59)

− 0.03 (− 0.96–0.89)

0.062

  1. OR odds ratio, CI confidence interval, SD standard deviation, CV coefficient of variation, VIM variability independent of the mean
  2. *Statistically significant p value (< 0.05); Mann-Whitney test