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Table 5 Day-to-day intra-individual variability Indices of CRP, PCT, and WBC for anastomotic leakage

From: Role of the triad of procalcitonin, C-reactive protein, and white blood cell count in the prediction of anastomotic leak following colorectal resections

Within table-individual variability No AL AL Mean difference (95% CI) p value
CRP SD 30.72 (24.9) 74.67 (33.8) 43.9 (32.4–55.5) < 0.001*
CV 0.68 (0.22) 0.93 (0.14) 0.25 (0.16–0.35) < 0.001*
VIM 31.90 (9.78) 41.45 (8.25) 9.56 (5.27–13.8) < 0.001*
PCT SD 0.66 (0.45) 2.27 (1.09) 1.61 (1.12–2.10) < 0.001*
CV 0.47 (0.14) 0.71 (0.21) 0.24 (0.14–0.33) < 0.001*
VIM 0.87 (0.37) 0.85 (0.27) − 0.02 (− 0.18–0.15) 0.673
WBC SD 1.25 (1.55) 1.92 (0.60) 0.67 (0.01–1.33) < 0.001*
CV 0.17 (0.13) 0.24 (0.06) 0.08 (0.02–0.13) < 0.001*
VIM 1.67 (2.19) 1.63 (0.59) − 0.03 (− 0.96–0.89) 0.062
  1. OR odds ratio, CI confidence interval, SD standard deviation, CV coefficient of variation, VIM variability independent of the mean
  2. *Statistically significant p value (< 0.05); Mann-Whitney test