|
Isolated time points
|
AUC
|
95% CI
|
Cutoff values
|
SN
|
SP
|
PPV
|
NPV
|
|---|
|
CRP (mg/L)
|
|
POD 1
|
0.51
|
0.44–0.58
|
12.5
|
90.9
|
24.0
|
12.6
|
95.7
|
|
POD 2
|
0.70*
|
0.63–0.76
|
62.6
|
81.8
|
67.2
|
23.1
|
96.9
|
|
POD 3
|
0.76*
|
0.69–0.81
|
114.1
|
81.1
|
85.2
|
40.0
|
97.5
|
|
POD 4
|
0.75*
|
0.68–0.81
|
168.4
|
72.7
|
94.5
|
61.5
|
96.6
|
|
POD 5
|
0.68*
|
0.61–0.74
|
210.5
|
59.1
|
97.8
|
76.5
|
95.2
|
|
PCT (ng/mL)
|
|
POD 1
|
0.73*
|
0.66–0.79
|
1.30
|
50.0
|
88.0
|
33.3
|
93.6
|
|
POD 2
|
0.73*
|
0.67–0.79
|
1.89
|
63.6
|
86.3
|
35.9
|
95.2
|
|
POD 3
|
0.84*
|
0.79–0.89
|
2.60
|
77.3
|
90.7
|
50.0
|
97.1
|
|
POD 4
|
0.85*
|
0.80–0.90
|
3.65
|
72.7
|
94.5
|
61.5
|
96.6
|
|
POD 5
|
0.89*
|
0.84–0.93
|
4.93
|
77.3
|
96.7
|
73.9
|
97.3
|
|
WBC (× 1000/mm3)
|
|
POD 1
|
0.50
|
0.45–0.59
|
6.11
|
90.9
|
30.6
|
13.6
|
96.6
|
|
POD 3
|
0.66*
|
0.59–0.73
|
7.50
|
91.0
|
41.5
|
15.7
|
97.4
|
|
POD 5
|
0.79*
|
0.73–0.85
|
9.02
|
86.4
|
71.0
|
26.4
|
97.7
|
- CRP C-reactive protein, PCT procalcitonin, WBC white blood cell count, SN sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, POD postoperative day
- *Statistically significant different AUC from the reference diagonal line at p values of less than 0.05
