Table 1 Baseline demographic and related clinical characteristics for patients diagnosed with colorectal cancer
Characteristics | No. of colorectal cancer patients SEER (2010–2012) | No. of colorectal cancer patients Dalian (2011–2015) | ||||
|---|---|---|---|---|---|---|
With TDs (N = 7096, 12.07%) | Without TDs (N = 51679, 87.92%) | p value | With TDs (N = 207, 27.90%) | Without TDs (N = 535,72.10%) | p value | |
Age, in years | < 0.001 | 0.826 | ||||
< 65 | 3263 (13.80) | 20379 (86.20) | 115 (27.58) | 302 (72.42) | ||
≥ 65 | 3833 (10.91) | 31300 (89.09) | 92 (28.31) | 233 (71.69) | ||
Sex | 0.217 | 0.011 | ||||
Male | 3450 (11.58) | 25530 (88.42) | 137 (31.42) | 299 (68.58) | ||
Female | 3046 (10.51) | 26149 (89.49) | 70 (22.89) | 236 (77.11) | ||
Race | 0.230 | |||||
White | 5687 (12.05) | 41510 (87.95) | — | — | ||
Black | 810 (12.29) | 5780 (87.71) | — | — | ||
Other | 559 (12.00) | 4389 (88.00) | — | — | ||
AJCC | < 0.001 | < 0.001 | ||||
I | 66 (0.47) | 13816 (99.53) | 3 (3.33) | 87 (96.67) | ||
II | 582 (3.02) | 18705 (96.98) | 58 (16.76) | 288 (83.24) | ||
III | 3855 (20.63) | 14830 (79.37) | 109 (44.49) | 136 (55.51) | ||
IV | 2573 (37.28) | 4328 (62.72) | 37 (60.66) | 24 (39.34) | ||
T stage | < 0.001 | < 0.001 | ||||
T1 | 104 (1.40) | 7318 (99.60) | 0 (0) | 19 (100) | ||
T2 | 258 (2.73) | 9198 (97.27) | 8 (9.30) | 78 (91.70) | ||
T3 | 4087 (12.55) | 28487 (87.45) | 6 (10.71) | 50 (89.29) | ||
T4 | 2647 (28.39) | 6676 (71.61) | 193 (30.22) | 388 (69.78) | ||
N stage | < 0.001 | <0.001 | ||||
N0 | 823 (2.39) | 33611 (97.61) | 70 (15.35) | 386 (84.65) | ||
N1 | 3095 (20.92) | 11695 (79.08) | 94 (42.53) | 127 (57.47) | ||
N2 | 3178 (33.27) | 6373 (66.73) | 43 (66.15) | 22 (33.85) | ||
M stage | < 0.001 | <0.001 | ||||
M0 | 4523 (8.72) | 47351 (91.28) | 151 (22.27) | 527 (77.73) | ||
M1 | 2573 (37.28) | 4328 (62.72) | 56 (87.50) | 8 (13.50) | ||
Primary site | < 0.001 | 0.199 | ||||
Colon | 5509 (11.84) | 40929 (88.16) | 99 (25.85) | 284 (74.15) | ||
Rectum | 1587 (12.97) | 10750 (87.03) | 108 (30.08) | 251 (69.92) | ||
Grade | < 0.001 | |||||
I | 274 (5.99) | 4300 (94.01) | — | — | ||
II | 4396 (10.33) | 38149 (89.67) | — | — | ||
III | 1909 (19.90) | 7683 (80.10) | — | — | ||
IV | 517 (25.05) | 1547 (84.95) | — | — | ||
Perineural invasion | < 0.001 | |||||
None | 4761 (9.11) | 47473 (90.89) | — | — | ||
Yes | 2335 (35.70) | 4206 (64.30) | — | — | ||
Liver metastasis | < 0.001 | < 0.001 | ||||
None | 5409 (10.04) | 48492 (89.96) | 153 (23.29) | 504 (76.71) | ||
Yes | 1687 (34.61) | 3187 (65.39) | 54 (63.53) | 31 (36.47) | ||
Lung metastasis | < 0.001 | |||||
None | 6736 (11.66) | 51015 (88.34) | — | — | ||
Yes | 360 (35.16) | 664 (64.84) | — | — | ||
Bone metastasis | < 0.001 | |||||
None | 7032 (12.00) | 51584 (88.00) | — | — | ||
Yes | 64 (40.25) | 95 (59.75) | — | — | ||
Brain metastasis | 0.002 | |||||
None | 7082 (12.06) | 51639 (87.94) | — | — | ||
Yes | 14 (25.93) | 40 (74.07) | — | — | ||