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Table 1 Clinicopathological parameters included in risk models for solitary fibrous tumor

From: Prognostic usefulness of a modified risk model for solitary fibrous tumor that includes the Ki-67 labeling index

Variable Patients, n (%) 5-year MFS (%)
(95% CI)
Log-rank
p value
Age (years)
 < 55 (score 0) 19 (44.2) 100 (a) 0.218
 ≥ 55 (score 1) 24 (55.8) 87.2 (60.2–96.8)  
Sex
 Male 21 (48.8) 85.6 (56.1–96.5) 0.121
 Female 22 (51.2) 100 (a)  
Location
 IT 10 (23.3) 100 (a) 0.229
 IA 12 (27.9) 87.5 (46.3–98.3)  
 CNS 6 (14.0) 100 (a)  
 Other 15 (34.9) 88.9 (50.0–98.5)  
Tumor size (cm)
 0–4.9 (score 0) 24 (55.8) 100 (a) 0.095
 5–9.9 (score 1) 10 (23.3) 100 (a)  
 10–14.9 (score 2) 3 (7.0) 100 (a)  
 ≥ 15 (score 3) 6 (14.9) 60.0 (20.0–90.0)  
Mitoses/mm2
 0 (score 0) 34 (79.1) 94.7 (70.6–99.3) 0.982
 0.5–1.5 (score 1) 4 (9.3) 100 (a)  
 ≥ 2 (score 2) 5 (11.6) 66.7 (15.4–95.7)  
Ki-67 LI (%)
 < 1 (score 0) 15 (34.9) 90.0 (53.3–98.6) 0.018
 1–10 (score 1) 24 (55.8) 100 (a)  
 ≥ 10 (score 2) 4 (9.3) 50.0 (5.8–94.1)  
Tumor necrosis (%)
 < 10 (score 0) 40 (93.0) 92.3 (73.5–98.1) 0.978
 ≥ 10 (score 1) 3 (7.0) 100 (a)  
Dedifferentiation
 Present 2 (4.7) 0 0.000
 Absent 41 (95.3) 95.7 (74.8–99.4)  
Three-variable risk model (age, size, mitoses)
 Low (0–2 points) 33 (76.7) 100 (a) 0.049
 Intermediate (3–4 points) 7 (16.3) 50.0 (5.9–94.1)  
 High (5–6 points) 3 (7.0) 66.7 (15.4–95.7)  
Four-variable risk model (age, size, mitoses, necrosis)
 Low (0–3 points) 37 (86.0) 100 (a) 0.060
 Intermediate (4–5 points) 4 (9.3) 50.0 (5.9–94.1)  
  High (6–7 points) 2 (4.7) 50.0 (5.9–94.1)  
Modified three-variable model (age, size, Ki-67 LI)
 Low risk (0–2 points) 29 (67.4) 100 (a) 0.006
  Intermediate/high risk (3–6 points) 14 (32.6) 74.1 (35.6–93.7)  
Modified four-variable model (age, size, Ki-67 LI, necrosis)
 Low risk (0–3 points) 35 (81.4) 100 (a) 0.022
 Intermediate/high risk (4–7 points) 8 (18.6) 62.5 (21.9–90.9)  
  1. CI confidence interval, CNS central nervous system, IA intra-abdominal, IT intrathoracic, LI labeling index, MFS metastasis-free survival
  2. a95% CI was not calculated because of no events until 5 years