Table 1 Demographics and clinical characteristics of patients with second primary renal cell carcinoma (2nd RCC) and first primary renal cell carcinoma (1st RCC)
From: A comprehensive analysis of renal cell carcinoma as first and second primary cancers
Characteristic | 2nd RCC | 1st RCC | p value | |
|---|---|---|---|---|
Patients | ||||
Number of patients | 113 | 749 | ||
Gender | Male | 67 (59.3%) | 452 (60.3%) | 0.83 |
Female | 46 (40.7%) | 297 (39.7%) | ||
Mean age, years (±SD) | 58.2 (±10.2) | 55.0 (±12.1) | 0.008 | |
Smoking history | Yes | 51 (45.1%) | 262 (35.0%) | 0.036 |
No | 62 (54.9%) | 487 (65.0%) | ||
Family history of tumor | Yes | 36 (31.9%) | 179 (23.9%) | 0.068 |
No | 77 (68.1%) | 570 (76.1%) | ||
Mean BMI, kg/m2 (±SD) | 23.9 (±3.2) | 23.9 (±3.4) | 1.00 | |
Disease | ||||
Symptom | Yes | 2 (1.8%) | 219 (29.2%) | <0.001 |
No | 111 (98.2%) | 530 (70.8%) | ||
Synchronous | 71 (62.8%) | – | – | |
Metachronous | 42 (37.2%) | – | ||
Mean interval between first extrarenal malignancies and renal cell carcinoma, months (range) | 33.9 (0–540) | – | – | |
Mean diameter of renal mass, cm (±SD ) | 3.6 (±1.6) | 4.7 (±2.5) | <0.001 | |
Renal surgery | Radical nephrectomy | 43 (39.8%) | 394 (52.6%) | 0.013 |
Partial nephrectomy | 65 (60.2%) | 355 (47.4%) | ||