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Table 1 Demographics and clinical characteristics of patients with second primary renal cell carcinoma (2nd RCC) and first primary renal cell carcinoma (1st RCC)

From: A comprehensive analysis of renal cell carcinoma as first and second primary cancers

Characteristic 2nd RCC 1st RCC p value
Patients
 Number of patients 113 749  
 Gender Male 67 (59.3%) 452 (60.3%) 0.83
Female 46 (40.7%) 297 (39.7%)
 Mean age, years (±SD) 58.2 (±10.2) 55.0 (±12.1) 0.008
 Smoking history Yes 51 (45.1%) 262 (35.0%) 0.036
No 62 (54.9%) 487 (65.0%)
 Family history of tumor Yes 36 (31.9%) 179 (23.9%) 0.068
No 77 (68.1%) 570 (76.1%)
 Mean BMI, kg/m2SD) 23.9 (±3.2) 23.9 (±3.4) 1.00
Disease
 Symptom Yes 2 (1.8%) 219 (29.2%) <0.001
No 111 (98.2%) 530 (70.8%)
 Synchronous 71 (62.8%)
 Metachronous 42 (37.2%)
 Mean interval between first extrarenal malignancies and renal cell carcinoma, months (range) 33.9 (0–540)
 Mean diameter of renal mass, cm (±SD ) 3.6 (±1.6) 4.7 (±2.5) <0.001
 Renal surgery Radical nephrectomy 43 (39.8%) 394 (52.6%) 0.013
Partial nephrectomy 65 (60.2%) 355 (47.4%)
  1. RCC renal cell carcinoma, BMI body mass index