Table 2 Univariate and multivariate analysis of overall pCR in patients with ER+, Her2− breast cancer (n = 273)

Age, years (≥ 45 vs < 45)

0.931 (0.403–2.154)

0.868

–

BMI, kg/m² (≥ 24 vs < 24)

1.012 (0.462–2.217)

0.975

–

Tumor location (right vs left)

0.914 (0.418–1.998)

0.822

–

Menopausal status (premenopausal vs postmenopausal)

1.971 (0.836–4.647)

0.121

–

 PLR (≥ 117.88 vs < 117.88)

1.637 (0.712–3.763)

0.246

–

 NLR (≥ 2.46 vs < 2.46)

0.485 (0.221–1.066)

0.072

0.335 (0.133–0.843)

0.020

 FBG (≥ 1.73 vs < 1.73)

2.312 (0.526–10.160)

0.267

–

Tumor size, cm

0.954

–

 < 2

1 (reference)

 2 ~ 5

0.886 (0.283–2.768)

 > 5

0.795 (0.184–3.436)

Lymph node status (cNX vs cN0)

0.929 (0.425–2.031)

0.854

–

Blood supply (abundant vs poor)

0.561 (0.256–1.229)

0.149

–

Histological grade

0.052

0.821

 I

1 (reference)

1 (reference)

 II

1.918 (0.244–15.056)

1.542 (0.162–14.664)

 III

6.333 (0.693–57.905)

2.070 (0.174–24.651)

ER (%)

0.006

0.011

  [1, 10]

1 (reference)

1 (reference)

  [10, 30]

0.293 (0.048–1.801)

0.117 (0.023–1.377)

  [30, 50]

0.670 (0.173–2.593)

0.673 (0.138–3.270)

  [50, 70]

0.244 (0.063–0.945)

0.289 (0.056–1.509)

 > 70

0.124 (0.035–0.443)

0.085 (0.017–0.433)

PgR (%)

0.003

0.006

 Negative

1 (reference)

1 (reference)

  [1, 10]

2.250 (0.802–6.310)

4.790 (1.316–17.431)

 > 10

0.419 (0.157–1.116)

0.932 (0.272–3.191)

Ki-67(%)

0.022

0.011

 < 20

1 (reference)

1 (reference)

  [20, 40)

4.378 (1.210–15.847)

6.964 (1.682–28.839)

  [40, 60)

7.467 (1.875–29.735)

11.316 (2.475–51.729)

 ≥ 60

8.711 (1.772–42.825)

14.444 (2.168–96.222)

P53 status (positive vs negative)

1.467 (0.570–3.771)

0.427

–