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Fig. 3 | World Journal of Surgical Oncology

Fig. 3

From: Circ_0047921 acts as the sponge of miR-1287-5p to stimulate lung cancer progression by regulating proliferation, migration, invasion, and glycolysis of lung cancer cells

Fig. 3

MiR-1287-5p was a direct target of circ_0047921. A The putative targets of circ_0047921 were predicted by Starbase 3.0 and circinteractome. B, C RT-qPCR assay was used to detect the expression level of miR-1287-5p in lung cancer tissues (NSCLC, N = 60) and corresponding controls (N = 60), as well as in BEAS-2B, A549, and H1299 cells. D Correlation analysis revealed a negative correlation between miR-1287-5p and circ_0047921 in tumor tissues. E The expression level of miR-1287-5p was examined by RT-qPCR assay in A549 and H1299 cells infected with si-NC or si-circ_0047921. F Binding regions between miR-1287-5p and circ_0047921 were shown. G, H The relative luciferase activity in A549 and H1299 cells was analyzed by dual-luciferase reporter assay. *P < 0.05

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