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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Circ_0047921 acts as the sponge of miR-1287-5p to stimulate lung cancer progression by regulating proliferation, migration, invasion, and glycolysis of lung cancer cells

Fig. 2

Effects of circ_0047921 inhibition on proliferation, migration, invasion, and EMT of lung cancer cells. AR A549 and H1299 cells were transfected with si-NC or si-circ_0047921. A, B The relative expression level of circ_0047921 was evaluated by RT-qPCR. C, D The growth curves of A549 and H1299 cells were measured by CCK8 assay. E, F Enumeration of Edu-positive cells was evaluated by Edu assay. G, J Transwell assay was performed to measure the migration and invasion abilities of A549 and H1299 cells. K, L Western blot analysis was carried out to show E-cadherin, Vimentin and N-cadherin levels in A549 and H1299 cells. M, P The glucose consumption and lactate production were determined by matched kits. Q, R GLUT1, HK2, and LDHA levels in A549 and H1299 cells were quantified by western blot. *P < 0.05

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