Primary intraosseous carcinoma in the pediatric and adolescent mandible

Table 2 Treatment outcomes of 10 pediatric patients with primary intraosseous carcinoma in the jaw

Case	Initial diagnosis	Initial treatment	Confirmed diagnosis	Definitive treatment	Cervical metastasis	Local recurrence	Salvage treatment	Follow-up duration	Survival status at the last F/U
1	N/S	N/S	N/S	Excision	Yes ^a	Yes	Radical excision/SND, RT ^a	27 months	Alive
2	N/S	N/S	N/S	Excision	Yes ^b	Yes	Mandibulectomy, SND	8 months	Dead
3	Dentigerous cyst	Incisional biopsy	Carcinoma	Mandibulectomy, SND	No	No	No	8 months	Alive
4	Odontogenic cyst	FNAC	Odontogenic cyst	Enucleation	N/S	No	No	16 months	Alive
5	N/S	N/S	N/S	Maxillectomy, RT	No	No	No	44 months	Alive
6	Follicular cyst	Enucleation with extraction	PIOC	Maxillectomy, reconstruction with iliac crest	No	No	No	10 years	Alive
7	More aggressive lesion than odontogenic cyst	Incisional biopsy with extraction	PIOC	Mandibulectomy, mRND, reconstruction with plate, RT	Yes	No	No	7 years	Alive
8	OKC	Enucleation with extraction	PIOC	Refer	N/S	N/S	N/S	N/S	N/S
9	Dentigerous cyst	Enucleation with extraction	PIOC	Maxillectomy, reconstruction with plate and iliac crest	No	No	No	6 years	Alive
10	N/S	N/S	N/S	Maxillectomy	N/S	No	No	5 years	Alive
11	OKC	Incisional biopsy	OKC	Enucleation with extraction	No	No	No	18 months	Alive
12	Odontogenic cyst	Enucleation with extraction	PIOC	Mandibulectomy, SND, reconstruction with FFF	No	Yes	CCRT	9 months ^c	Alive

F/U follow-up, N/S not specified, OKC odontogenic keratocyst, FNAC fine needle aspiration cytology, PIOC primary intraosseous carcinoma, SND selective neck dissection, mRND modified radical neck dissection, RT radiation therapy, CCRT concurrent chemo-radiation therapy, FFF fibular free flap
^aAt second recurrence
^bAt recurrence
^cRecurred but lost to follow-up

ISSN: 1477-7819