Table 4 Total OR and 95% CI of three MiRNA polymorphisms in relation to cervical cancer susceptibility

MiRNA-146a rs2910164

5

CC vs. GG

0.713 [0.505-1.006]

1.93

0.054

12.84

68.8

0.012

CG vs. GG

0.920 [0.790-1.080]

1.03

0.304

7.08

43.5

0.132

CG+CC vs. GG

0.807 [0.627-1.038]

1.67

0.095

9.84

59.4

0.043

CC vs. GG+CG

0.804 [0.652-0.992]

2.04

0.042

8.2

51.2

0.085

CC+GG vs. CG

0.939 [0.834-1.056]

1.05

0.293

2.42

0

0.659

C vs. G

0.845 [0.721-0.991]

2.07

0.038

11.46

65.1

0.022

MiRNA-499 rs3746444

3

CC vs. TT

0.958 [0.663-1.383]

0.23

0.818

0.46

0

0.794

CT vs. TT

1.173 [0.678-2.032]

0.57

0.568

12.04

83.4

0.002

CT+CC vs. TT

1.140 [0.719-1.809]

0.56

0.577

9.65

79.3

0.008

CC vs. CT+TT

0.966 [0.705-1.324]

0.22

0.829

0.68

0

0.71

TT+CC vs. CT

0.833 [0.511-1.358]

0.73

0.464

12.2

83.6

0.002

C vs. T

1.079 [0.832-1.401]

0.57

0.566

5.71

65

0.058

MiRNA-196a2 rs11614913

6

TT vs.CC

0.641 [0.447-0.919]

2.42

0.016

22.99

78.2

< 0.001

CT vs. CC

0.922 [0.804-1.056]

1.17

0.24

3.68

0

0.597

CT+TT vs. CC

0.795 [0.636-0.994]

2.01

0.045

12.71

60.7

0.026

TT vs. CT+CC

0.698 [0.532-0.917]

2.58

0.01

20.93

76.1

0.001

TT+CC vs. CT

0.917 [0.824-1.020]

1.6

0.11

1.12

0

0.952

T vs. C

0.783 [0.643-0.954]

2.43

0.015

28.59

82.5

< 0.001